Hofele R - Search Results

1

Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.

Hamann F, Schmitt A, Favretto F, Hofele R, Neumann P, Xiang S, Urlaub H, Zweckstetter M, Ficner R. Hamann F, et al. Among authors: hofele r. Proc Natl Acad Sci U S A. 2020 Feb 11;117(6):2948-2956. doi: 10.1073/pnas.1907960117. Epub 2020 Jan 23. Proc Natl Acad Sci U S A. 2020. PMID: 31974312 Free PMC article.

2

Insights into the activation of the helicase Prp43 by biochemical studies and structural mass spectrometry.

Christian H, Hofele RV, Urlaub H, Ficner R. Christian H, et al. Among authors: hofele rv. Nucleic Acids Res. 2014 Jan;42(2):1162-79. doi: 10.1093/nar/gkt985. Epub 2013 Oct 27. Nucleic Acids Res. 2014. PMID: 24165877 Free PMC article.

3

Tau stabilizes microtubules by binding at the interface between tubulin heterodimers.

Kadavath H, Hofele RV, Biernat J, Kumar S, Tepper K, Urlaub H, Mandelkow E, Zweckstetter M. Kadavath H, et al. Among authors: hofele rv. Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):7501-6. doi: 10.1073/pnas.1504081112. Epub 2015 Jun 1. Proc Natl Acad Sci U S A. 2015. PMID: 26034266 Free PMC article.

4

Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export.

Port SA, Monecke T, Dickmanns A, Spillner C, Hofele R, Urlaub H, Ficner R, Kehlenbach RH. Port SA, et al. Among authors: hofele r. Cell Rep. 2015 Oct 27;13(4):690-702. doi: 10.1016/j.celrep.2015.09.042. Epub 2015 Oct 17. Cell Rep. 2015. PMID: 26489467 Free article.

5

The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes.

De I, Bessonov S, Hofele R, dos Santos K, Will CL, Urlaub H, Lührmann R, Pena V. De I, et al. Among authors: hofele r. Nat Struct Mol Biol. 2015 Feb;22(2):138-44. doi: 10.1038/nsmb.2951. Epub 2015 Jan 19. Nat Struct Mol Biol. 2015. PMID: 25599396

6

Structural basis for the regulatory interaction of the methylglyoxal synthase MgsA with the carbon flux regulator Crh in Bacillus subtilis.

Dickmanns A, Zschiedrich CP, Arens J, Parfentev I, Gundlach J, Hofele R, Neumann P, Urlaub H, Görke B, Ficner R, Stülke J. Dickmanns A, et al. Among authors: hofele r. J Biol Chem. 2018 Apr 20;293(16):5781-5792. doi: 10.1074/jbc.RA117.001289. Epub 2018 Mar 7. J Biol Chem. 2018. PMID: 29514981 Free PMC article.

7

Molecular architecture of the human 17S U2 snRNP.

Zhang Z, Will CL, Bertram K, Dybkov O, Hartmuth K, Agafonov DE, Hofele R, Urlaub H, Kastner B, Lührmann R, Stark H. Zhang Z, et al. Among authors: hofele r. Nature. 2020 Jul;583(7815):310-313. doi: 10.1038/s41586-020-2344-3. Epub 2020 Jun 3. Nature. 2020. PMID: 32494006

8

Molecular architecture of the human U4/U6.U5 tri-snRNP.

Agafonov DE, Kastner B, Dybkov O, Hofele RV, Liu WT, Urlaub H, Lührmann R, Stark H. Agafonov DE, et al. Among authors: hofele rv. Science. 2016 Mar 25;351(6280):1416-20. doi: 10.1126/science.aad2085. Epub 2016 Feb 18. Science. 2016. PMID: 26912367

9

Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex.

Oroz J, Chang BJ, Wysoczanski P, Lee CT, Pérez-Lara Á, Chakraborty P, Hofele RV, Baker JD, Blair LJ, Biernat J, Urlaub H, Mandelkow E, Dickey CA, Zweckstetter M. Oroz J, et al. Among authors: hofele rv. Nat Commun. 2018 Oct 31;9(1):4532. doi: 10.1038/s41467-018-06880-0. Nat Commun. 2018. PMID: 30382094 Free PMC article.

10

Burial of the polymorphic residue 129 in amyloid fibrils of prion stop mutants.

Skora L, Fonseca-Ornelas L, Hofele RV, Riedel D, Giller K, Watzlawik J, Schulz-Schaeffer WJ, Urlaub H, Becker S, Zweckstetter M. Skora L, et al. J Biol Chem. 2013 Feb 1;288(5):2994-3002. doi: 10.1074/jbc.M112.423715. Epub 2012 Dec 3. J Biol Chem. 2013. PMID: 23209282 Free PMC article.

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