Hoffman WP - Search Results

1

Quantitative assessment of cumulative carcinogenic risk for multiple genotoxic impurities in a new drug substance.

Bercu JP, Hoffman WP, Lee C, Ness DK. Bercu JP, et al. Among authors: hoffman wp. Regul Toxicol Pharmacol. 2008 Aug;51(3):270-7. doi: 10.1016/j.yrtph.2008.04.011. Epub 2008 Apr 27. Regul Toxicol Pharmacol. 2008. PMID: 18550240

2

An evaluation of the twofold rule for assessing a positive response in the L5178Y TK+/- mouse lymphoma assay.

Oberly TJ, Hoffman WP, Garriott ML. Oberly TJ, et al. Among authors: hoffman wp. Mutat Res. 1996 Aug 12;369(3-4):221-32. doi: 10.1016/s0165-1218(96)90027-0. Mutat Res. 1996. PMID: 8792840

3

Comparative effects of disulfiram and N-methyltetrazolethiol on spermatogenic development in young CD rats.

Hoover DM, Hoyt JA, Seyler DE, Abbott DL, Hoffman WP, Buening MK. Hoover DM, et al. Among authors: hoffman wp. Toxicol Appl Pharmacol. 1991 Jan;107(1):164-72. doi: 10.1016/0041-008x(91)90340-k. Toxicol Appl Pharmacol. 1991. PMID: 1987655

4

Overall type I error rate and power of multiple Dunnett's tests on rodent body weights in toxicology studies.

Hoffman WP, Recknor J, Lee C. Hoffman WP, et al. J Biopharm Stat. 2008;18(5):883-900. doi: 10.1080/10543400802287420. J Biopharm Stat. 2008. PMID: 18781523

5

A protocol for the in vitro micronucleus test. II. Contributions to the validation of a protocol suitable for regulatory submissions from an examination of 10 chemicals with different mechanisms of action and different levels of activity.

Phelps JB, Garriott ML, Hoffman WP. Phelps JB, et al. Among authors: hoffman wp. Mutat Res. 2002 Nov 26;521(1-2):103-12. doi: 10.1016/s1383-5718(02)00221-8. Mutat Res. 2002. PMID: 12438008

6

Analysis of rodent growth data in toxicology studies.

Hoffman WP, Ness DK, van Lier RB. Hoffman WP, et al. Toxicol Sci. 2002 Apr;66(2):313-9. doi: 10.1093/toxsci/66.2.313. Toxicol Sci. 2002. PMID: 11896298

7

A protocol for the in vitro micronucleus test. I. Contributions to the development of a protocol suitable for regulatory submissions from an examination of 16 chemicals with different mechanisms of action and different levels of activity.

Garriott ML, Phelps JB, Hoffman WP. Garriott ML, et al. Among authors: hoffman wp. Mutat Res. 2002 May 27;517(1-2):123-34. doi: 10.1016/s1383-5718(02)00059-1. Mutat Res. 2002. PMID: 12034314

8

Effects of inhalation exposures to an M1-receptor agonist on ventilation in rhesus monkeys.

Allen DL, Leiter PA, Tielking RL, Hoffman WP, Vidyashankar AN, van Lier RB, Wolff RK. Allen DL, et al. Among authors: hoffman wp. Drug Chem Toxicol. 1999 Nov;22(4):595-611. doi: 10.3109/01480549908993170. Drug Chem Toxicol. 1999. PMID: 10536751

9

Validation of an automated image analysis micronucleus scoring system.

Parton JW, Hoffman WP, Garriott ML. Parton JW, et al. Among authors: hoffman wp. Mutat Res. 1996 Aug;370(1):65-73. doi: 10.1016/s0165-1218(96)90128-7. Mutat Res. 1996. PMID: 8830808

10

Duration of clinical effects and absence of referred hyperalgesia after femoral vein cannulation in rats.

Cooper DM, Hoffman W, Wheat N, Lee HY. Cooper DM, et al. Comp Med. 2005 Oct;55(5):440-4. Comp Med. 2005. PMID: 16270900

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