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SUMO meets meiosis: an encounter at the synaptonemal complex: SUMO chains and sumoylated proteins suggest that heterogeneous and complex interactions lie at the centre of the synaptonemal complex.
Watts FZ, Hoffmann E. Watts FZ, et al. Among authors: hoffmann e. Bioessays. 2011 Jul;33(7):529-37. doi: 10.1002/bies.201100002. Epub 2011 May 17. Bioessays. 2011. PMID: 21590786 Review.
The synaptonemal complex protein, Zip1, promotes the segregation of nonexchange chromosomes at meiosis I.
Newnham L, Jordan P, Rockmill B, Roeder GS, Hoffmann E. Newnham L, et al. Among authors: hoffmann e. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):781-5. doi: 10.1073/pnas.0913435107. Epub 2009 Dec 22. Proc Natl Acad Sci U S A. 2010. PMID: 20080752 Free PMC article.
Ipl1/Aurora B kinase coordinates synaptonemal complex disassembly with cell cycle progression and crossover formation in budding yeast meiosis.
Jordan P, Copsey A, Newnham L, Kolar E, Lichten M, Hoffmann E. Jordan P, et al. Among authors: hoffmann e. Genes Dev. 2009 Sep 15;23(18):2237-51. doi: 10.1101/gad.536109. Genes Dev. 2009. PMID: 19759266 Free PMC article.
Temperature-dependent modulation of chromosome segregation in msh4 mutants of budding yeast.
Chan AC, Borts RH, Hoffmann E. Chan AC, et al. Among authors: hoffmann e. PLoS One. 2009 Oct 9;4(10):e7284. doi: 10.1371/journal.pone.0007284. PLoS One. 2009. PMID: 19816584 Free PMC article.
Ipl1/Aurora kinase suppresses S-CDK-driven spindle formation during prophase I to ensure chromosome integrity during meiosis.
Newnham L, Jordan PW, Carballo JA, Newcombe S, Hoffmann E. Newnham L, et al. Among authors: hoffmann e. PLoS One. 2013 Dec 27;8(12):e83982. doi: 10.1371/journal.pone.0083982. eCollection 2013. PLoS One. 2013. PMID: 24386320 Free PMC article.
Smc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisions.
Copsey A, Tang S, Jordan PW, Blitzblau HG, Newcombe S, Chan AC, Newnham L, Li Z, Gray S, Herbert AD, Arumugam P, Hochwagen A, Hunter N, Hoffmann E. Copsey A, et al. Among authors: hoffmann e. PLoS Genet. 2013;9(12):e1004071. doi: 10.1371/journal.pgen.1004071. Epub 2013 Dec 26. PLoS Genet. 2013. PMID: 24385939 Free PMC article.
FindFoci: a focus detection algorithm with automated parameter training that closely matches human assignments, reduces human inconsistencies and increases speed of analysis.
Herbert AD, Carr AM, Hoffmann E. Herbert AD, et al. Among authors: hoffmann e. PLoS One. 2014 Dec 5;9(12):e114749. doi: 10.1371/journal.pone.0114749. eCollection 2014. PLoS One. 2014. PMID: 25478967 Free PMC article.
Gold amides as anticancer drugs: synthesis and activity studies.
Newcombe S, Bobin M, Shrikhande A, Gallop C, Pace Y, Yong H, Gates R, Chaudhuri S, Roe M, Hoffmann E, Viseux EM. Newcombe S, et al. Among authors: hoffmann e. Org Biomol Chem. 2013 May 21;11(19):3255-60. doi: 10.1039/c3ob27460h. Epub 2013 Apr 15. Org Biomol Chem. 2013. PMID: 23584015
The G67E mutation in hMLH1 is associated with an unusual presentation of Lynch syndrome.
Clyne M, Offman J, Shanley S, Virgo JD, Radulovic M, Wang Y, Ardern-Jones A, Eeles R, Hoffmann E, Yu VP. Clyne M, et al. Among authors: hoffmann e. Br J Cancer. 2009 Jan 27;100(2):376-80. doi: 10.1038/sj.bjc.6604860. Epub 2009 Jan 13. Br J Cancer. 2009. PMID: 19142183 Free PMC article.
Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control.
Gallina I, Colding C, Henriksen P, Beli P, Nakamura K, Offman J, Mathiasen DP, Silva S, Hoffmann E, Groth A, Choudhary C, Lisby M. Gallina I, et al. Among authors: hoffmann e. Nat Commun. 2015 Mar 30;6:6533. doi: 10.1038/ncomms7533. Nat Commun. 2015. PMID: 25817432 Free PMC article.
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