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The selective alpha7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain slices and restores auditory gating deficits in anesthetized rats.
Hajós M, Hurst RS, Hoffmann WE, Krause M, Wall TM, Higdon NR, Groppi VE. Hajós M, et al. Among authors: hoffmann we. J Pharmacol Exp Ther. 2005 Mar;312(3):1213-22. doi: 10.1124/jpet.104.076968. Epub 2004 Nov 2. J Pharmacol Exp Ther. 2005. PMID: 15523001
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