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mu-Opioid receptor forms a functional heterodimer with cannabinoid CB1 receptor: electrophysiological and FRET assay analysis.
Hojo M, Sudo Y, Ando Y, Minami K, Takada M, Matsubara T, Kanaide M, Taniyama K, Sumikawa K, Uezono Y. Hojo M, et al. J Pharmacol Sci. 2008 Nov;108(3):308-19. doi: 10.1254/jphs.08244fp. Epub 2008 Nov 13. J Pharmacol Sci. 2008. PMID: 19008645
Experiments with endogenous Gi/o protein inactivation by pertussis toxin (PTX) supported the functional heterodimerization of muOR/CB1R through PTX-insensitive Gqi5(m) fused to each receptor. ...
Experiments with endogenous Gi/o protein inactivation by pertussis toxin (PTX) supported the functional heterodimerization of muOR/CB1R thro …
Possible involvement of β-endorphin in a loss of the coordinated balance of μ-opioid receptors trafficking processes by fentanyl.
Imai S, Sudo Y, Nakamura A, Ozeki A, Asato M, Hojo M, Devi LA, Kuzumaki N, Suzuki T, Uezono Y, Narita M. Imai S, et al. Among authors: Hojo M. Synapse. 2011 Sep;65(9):962-6. doi: 10.1002/syn.20930. Epub 2011 Apr 11. Synapse. 2011. PMID: 21437993 Free PMC article. No abstract available.
S(+)-ketamine suppresses desensitization of γ-aminobutyric acid type B receptor-mediated signaling by inhibition of the interaction of γ-aminobutyric acid type B receptors with G protein-coupled receptor kinase 4 or 5.
Ando Y, Hojo M, Kanaide M, Takada M, Sudo Y, Shiraishi S, Sumikawa K, Uezono Y. Ando Y, et al. Among authors: Hojo M. Anesthesiology. 2011 Feb;114(2):401-11. doi: 10.1097/ALN.0b013e318204e003. Anesthesiology. 2011. PMID: 21245733
Efficacy and Safety of Oxycodone Injection for Relieving Cancer Pain: A Study in Japan Consisting of Two Open Trials for Intravenous and Subcutaneous Administration.
Yoshimoto T, Ryu E, Tomiyasu S, Hojo M, Kokubun H, Matoba M. Yoshimoto T, et al. Among authors: Hojo M. Biol Pharm Bull. 2018 Jun 1;41(6):850-857. doi: 10.1248/bpb.b17-00728. Epub 2018 Mar 10. Biol Pharm Bull. 2018. PMID: 29526884 Clinical Trial.
Possible involvement of prolonging spinal µ-opioid receptor desensitization in the development of antihyperalgesic tolerance to µ-opioids under a neuropathic pain-like state.
Narita M, Imai S, Nakamura A, Ozeki A, Asato M, Rahmadi M, Sudo Y, Hojo M, Uezono Y, Devi LA, Kuzumaki N, Suzuki T. Narita M, et al. Among authors: Hojo M. Addict Biol. 2013 Jul;18(4):614-22. doi: 10.1111/j.1369-1600.2011.00354.x. Epub 2011 Aug 4. Addict Biol. 2013. PMID: 21812868 Free PMC article.
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