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Functions and effectors of the Salmonella pathogenicity island 2 type III secretion system.
Waterman SR, Holden DW. Waterman SR, et al. Among authors: holden dw. Cell Microbiol. 2003 Aug;5(8):501-11. doi: 10.1046/j.1462-5822.2003.00294.x. Cell Microbiol. 2003. PMID: 12864810 Review.
SseA is a chaperone for the SseB and SseD translocon components of the Salmonella pathogenicity-island-2-encoded type III secretion system.
Ruiz-Albert J, Mundy R, Yu XJ, Beuzón CR, Holden DW. Ruiz-Albert J, et al. Among authors: holden dw. Microbiology (Reading). 2003 May;149(Pt 5):1103-1111. doi: 10.1099/mic.0.26190-0. Microbiology (Reading). 2003. PMID: 12724372
The translocated Salmonella effector proteins SseF and SseG interact and are required to establish an intracellular replication niche.
Deiwick J, Salcedo SP, Boucrot E, Gilliland SM, Henry T, Petermann N, Waterman SR, Gorvel JP, Holden DW, Méresse S. Deiwick J, et al. Among authors: holden dw. Infect Immun. 2006 Dec;74(12):6965-72. doi: 10.1128/IAI.00648-06. Epub 2006 Oct 2. Infect Immun. 2006. PMID: 17015457 Free PMC article.
Identification of salmonella pathogenicity island-2 type III secretion system effectors involved in intramacrophage replication of S. enterica serovar typhimurium: implications for rational vaccine design.
Figueira R, Watson KG, Holden DW, Helaine S. Figueira R, et al. Among authors: holden dw. mBio. 2013 Apr 16;4(2):e00065. doi: 10.1128/mBio.00065-13. mBio. 2013. PMID: 23592259 Free PMC article.
Functions of the Salmonella pathogenicity island 2 (SPI-2) type III secretion system effectors.
Figueira R, Holden DW. Figueira R, et al. Among authors: holden dw. Microbiology (Reading). 2012 May;158(Pt 5):1147-1161. doi: 10.1099/mic.0.058115-0. Epub 2012 Mar 15. Microbiology (Reading). 2012. PMID: 22422755 Review.
SlyA regulates function of Salmonella pathogenicity island 2 (SPI-2) and expression of SPI-2-associated genes.
Linehan SA, Rytkönen A, Yu XJ, Liu M, Holden DW. Linehan SA, et al. Among authors: holden dw. Infect Immun. 2005 Jul;73(7):4354-62. doi: 10.1128/IAI.73.7.4354-4362.2005. Infect Immun. 2005. PMID: 15972530 Free PMC article.
SsaM and SpiC interact and regulate secretion of Salmonella pathogenicity island 2 type III secretion system effectors and translocators.
Yu XJ, Liu M, Holden DW. Yu XJ, et al. Among authors: holden dw. Mol Microbiol. 2004 Nov;54(3):604-19. doi: 10.1111/j.1365-2958.2004.04297.x. Mol Microbiol. 2004. PMID: 15491354
SseG, a virulence protein that targets Salmonella to the Golgi network.
Salcedo SP, Holden DW. Salcedo SP, et al. Among authors: holden dw. EMBO J. 2003 Oct 1;22(19):5003-14. doi: 10.1093/emboj/cdg517. EMBO J. 2003. PMID: 14517239 Free PMC article.
The roles of SsrA-SsrB and OmpR-EnvZ in the regulation of genes encoding the Salmonella typhimurium SPI-2 type III secretion system.
Garmendia J, Beuzón CR, Ruiz-Albert J, Holden DW. Garmendia J, et al. Among authors: holden dw. Microbiology (Reading). 2003 Sep;149(Pt 9):2385-2396. doi: 10.1099/mic.0.26397-0. Microbiology (Reading). 2003. PMID: 12949164
Salmonella pathogenicity island-2 and anticancer activity in mice.
Pawelek JM, Sodi S, Chakraborty AK, Platt JT, Miller S, Holden DW, Hensel M, Low KB. Pawelek JM, et al. Among authors: holden dw. Cancer Gene Ther. 2002 Oct;9(10):813-8. doi: 10.1038/sj.cgt.7700501. Cancer Gene Ther. 2002. PMID: 12224021
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