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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1996 1
1997 3
1998 5
1999 4
2000 5
2001 1
2002 4
2003 3
2004 3
2005 5
2006 7
2007 5
2008 6
2009 5
2010 4
2011 7
2012 5
2013 9
2014 6
2015 6
2016 7
2017 5
2018 2
2019 1
2020 3
2021 7
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105 results
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Page 1
Soluble PD-L1: a potential immune marker for HIV-1 infection and virological failure.
Avendaño-Ortiz J, Rubio-Garrido M, Lozano-Rodríguez R, Del Romero J, Rodríguez C, Moreno S, Aguirre LA, Holguín Á, López-Collazo E. Avendaño-Ortiz J, et al. Among authors: holguin a. Medicine (Baltimore). 2020 May;99(20):e20065. doi: 10.1097/MD.0000000000020065. Medicine (Baltimore). 2020. PMID: 32443313 Free PMC article.
Despite viral control, basal chronic inflammation and its related comorbidities remain unsolved problems among HIV-infected individuals. Soluble factors derived from myeloid cells have emerged as potent markers associated with HIV-related comorbidities and mortality …
Despite viral control, basal chronic inflammation and its related comorbidities remain unsolved problems among HIV-infected individua …
Phylogenetic and demographic characterization of HIV-1 transmission in Madrid, Spain.
Yebra G, Holguín A, Pillay D, Hué S. Yebra G, et al. Among authors: holguin a. Infect Genet Evol. 2013 Mar;14:232-9. doi: 10.1016/j.meegid.2012.12.006. Epub 2013 Jan 2. Infect Genet Evol. 2013. PMID: 23291408
The Community of Madrid represents a challenge for the control of HIV epidemic in Spain given its high HIV prevalence and increasing proportion of immigrant people among HIV-infected population. METHODS: We applied maximum likelihood methods and Bayesi …
The Community of Madrid represents a challenge for the control of HIV epidemic in Spain given its high HIV prevalence a …
Molecular surveillance of HIV-1 in Madrid, Spain: a phylogeographic analysis.
González-Alba JM, Holguín A, Garcia R, García-Bujalance S, Alonso R, Suárez A, Delgado R, Cardeñoso L, González R, García-Bermejo I, Portero F, de Mendoza C, González-Candelas F, Galán JC. González-Alba JM, et al. Among authors: holguin a. J Virol. 2011 Oct;85(20):10755-63. doi: 10.1128/JVI.00454-11. Epub 2011 Jul 27. J Virol. 2011. PMID: 21795343 Free PMC article.
In recent years, Spain has become one of Europe's main destinations for immigrants and one of the western European countries with the highest rates of HIV-positive patients. Using a phylogeographic approach, we have analyzed the relationship between HIV-1 var …
In recent years, Spain has become one of Europe's main destinations for immigrants and one of the western European countries with the …
Trends in Drug Resistance Prevalence, HIV-1 Variants and Clinical Status in HIV-1-infected Pediatric Population in Madrid: 1993 to 2015 Analysis.
Rojas Sánchez P, Domínguez S, Jiménez De Ory S, Prieto L, Rojo P, Mellado P, Navarro M, Delgado R, Ramos JT, Holguín Á; Madrid Cohort of HIV-1 Infected Children and Adolescents Integrated in the Pediatric Branch of the Spanish National AIDS Network (CoRISPe). Rojas Sánchez P, et al. Among authors: holguin a. Pediatr Infect Dis J. 2018 Mar;37(3):e48-e57. doi: 10.1097/INF.0000000000001760. Pediatr Infect Dis J. 2018. PMID: 28991889
BACKGROUND: The expanded use of long-term antiretroviral treatments in infected children may exacerbate the problem of drug resistance mutations selection, which can compromise treatment efficiency. OBJECTIVE: We describe the temporal trends of HIV drug resistance mutation …
BACKGROUND: The expanded use of long-term antiretroviral treatments in infected children may exacerbate the problem of drug resistance mutat …
Impact of lopinavir-ritonavir exposure in HIV-1 infected children and adolescents in Madrid, Spain during 2000-2014.
Rojas Sánchez P, Prieto L, Jiménez De Ory S, Fernández Cooke E, Navarro ML, Ramos JT, Holguín Á; Madrid Cohort of HIV-1 Infected Children and Adolescents Integrated in the Paediatric Branch of the Spanish National AIDS Network (CoRISPe). Rojas Sánchez P, et al. Among authors: holguin a. PLoS One. 2017 Mar 28;12(3):e0173168. doi: 10.1371/journal.pone.0173168. eCollection 2017. PLoS One. 2017. PMID: 28350802 Free PMC article.
METHODOLOGY: Patients from the Madrid Cohort of HIV-1-infected-children and adolescents exposed to LPV/r as different line therapy during 2000-2014 were selected. ...Patients were mainly Spaniards (81.9%), perinatally infected (96.5%) with subtype-B (65.3%) and H
METHODOLOGY: Patients from the Madrid Cohort of HIV-1-infected-children and adolescents exposed to LPV/r as different line the …
Current and historic HIV-1 molecular epidemiology in paediatric and adult population from Kinshasa in the Democratic Republic of Congo.
Rubio-Garrido M, González-Alba JM, Reina G, Ndarabu A, Barquín D, Carlos S, Galán JC, Holguín Á. Rubio-Garrido M, et al. Among authors: holguin a. Sci Rep. 2020 Oct 28;10(1):18461. doi: 10.1038/s41598-020-74558-z. Sci Rep. 2020. PMID: 33116151 Free PMC article. Clinical Trial.
HIV-1 diversity may impact monitoring and vaccine development. We describe the most recent data of HIV-1 variants and their temporal trends in the Democratic Republic of Congo (DRC) from 1976 to 2018 and in Kinshasa from 1983-2018. HIV-1 pol sequencing from d
HIV-1 diversity may impact monitoring and vaccine development. We describe the most recent data of HIV-1 variants and their te
Drug resistance prevalence and HIV-1 variant characterization in the naive and pretreated HIV-1-infected paediatric population in Madrid, Spain.
de Mulder M, Yebra G, Martín L, Prieto L, Mellado MJ, Rojo P, Muñoz-Fernández MÁ, Jiménez de Ory S, Ramos JT, Holguín A; Madrid cohort of HIV-infected children. de Mulder M, et al. Among authors: holguin a. J Antimicrob Chemother. 2011 Oct;66(10):2362-71. doi: 10.1093/jac/dkr305. Epub 2011 Aug 2. J Antimicrob Chemother. 2011. PMID: 21810838
BACKGROUND: Drug resistance mutations affect antiretroviral therapy (ART) effectiveness in HIV-1-infected children, compromising long-term therapy. HIV-1 variants and drug resistance mutations were identified in HIV-infected children from Madrid, Spain …
BACKGROUND: Drug resistance mutations affect antiretroviral therapy (ART) effectiveness in HIV-1-infected children, compromising long …
Clinical and virologic follow-up in perinatally HIV-1-infected children and adolescents in Madrid with triple-class antiretroviral drug-resistant viruses.
Rojas Sánchez P, de Mulder M, Fernandez-Cooke E, Prieto L, Rojo P, Jiménez de Ory S, José Mellado M, Navarro M, Tomas Ramos J, Holguín Á; Madrid Cohort of HIV-Infected Children and Adolescents Integrated in the Paediatric Branch of the Spanish National AIDS Network (CoRISPe). Rojas Sánchez P, et al. Among authors: holguin a. Clin Microbiol Infect. 2015 Jun;21(6):605.e1-9. doi: 10.1016/j.cmi.2015.02.003. Epub 2015 Feb 11. Clin Microbiol Infect. 2015. PMID: 25680310 Free article.
Drug resistance mutations compromise the success of antiretroviral treatment in human immunodeficiency virus type 1 (HIV-1)-infected children. We report the virologic and clinical follow-up of the Madrid cohort of perinatally HIV-infected children and adolesc …
Drug resistance mutations compromise the success of antiretroviral treatment in human immunodeficiency virus type 1 (HIV-1)-infected …
Reconstructing the timing and dispersion routes of HIV-1 subtype B epidemics in the Caribbean and Central America: a phylogenetic story.
Pagán I, Holguín A. Pagán I, et al. Among authors: holguin a. PLoS One. 2013 Jul 9;8(7):e69218. doi: 10.1371/journal.pone.0069218. Print 2013. PLoS One. 2013. PMID: 23874917 Free PMC article.
The Caribbean and Central America are among the regions with highest HIV-1B prevalence worldwide. Despite of this high virus burden, little is known about the timing and the migration patterns of HIV-1B in these regions. ...Timing of HIV-1B introduction and v …
The Caribbean and Central America are among the regions with highest HIV-1B prevalence worldwide. Despite of this high virus burden, …
Drug resistance in the HIV-1-infected paediatric population worldwide: a systematic review.
Rojas Sánchez P, Holguín A. Rojas Sánchez P, et al. Among authors: holguin a. J Antimicrob Chemother. 2014 Aug;69(8):2032-42. doi: 10.1093/jac/dku104. Epub 2014 Apr 30. J Antimicrob Chemother. 2014. PMID: 24788658 Review.
BACKGROUND: Drug resistance monitoring of the paediatric HIV-1-infected population is required to optimize treatment success and preserve future treatment options. OBJECTIVES: To explore the current knowledge of HIV drug resistance (HIVDR) in naive and pretreated …
BACKGROUND: Drug resistance monitoring of the paediatric HIV-1-infected population is required to optimize treatment success and pres …
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