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Cerebrospinal fluid and plasma distribution of myo-inositol and other polyols in Alzheimer disease.
Shetty HU, Holloway HW, Schapiro MB. Shetty HU, et al. Among authors: holloway hw. Clin Chem. 1996 Feb;42(2):298-302. Clin Chem. 1996. PMID: 8595727
Design, synthesis and biological assessment of novel N-substituted 3-(phthalimidin-2-yl)-2,6-dioxopiperidines and 3-substituted 2,6-dioxopiperidines for TNF-α inhibitory activity.
Luo W, Yu QS, Salcedo I, Holloway HW, Lahiri DK, Brossi A, Tweedie D, Greig NH. Luo W, et al. Among authors: holloway hw. Bioorg Med Chem. 2011 Jul 1;19(13):3965-72. doi: 10.1016/j.bmc.2011.05.029. Epub 2011 May 23. Bioorg Med Chem. 2011. PMID: 21658960 Free PMC article.
Long-acting anticholinesterases for myasthenia gravis: synthesis and activities of quaternary phenylcarbamates of neostigmine, pyridostigmine and physostigmine.
Yu QS, Holloway HW, Luo W, Lahiri DK, Brossi A, Greig NH. Yu QS, et al. Among authors: holloway hw. Bioorg Med Chem. 2010 Jul 1;18(13):4687-93. doi: 10.1016/j.bmc.2010.05.022. Epub 2010 May 12. Bioorg Med Chem. 2010. PMID: 20627738 Free PMC article.
Inhibition of human acetyl- and butyrylcholinesterase by novel carbamates of (-)- and (+)-tetrahydrofurobenzofuran and methanobenzodioxepine.
Luo W, Yu QS, Kulkarni SS, Parrish DA, Holloway HW, Tweedie D, Shafferman A, Lahiri DK, Brossi A, Greig NH. Luo W, et al. Among authors: holloway hw. J Med Chem. 2006 Apr 6;49(7):2174-85. doi: 10.1021/jm050578p. J Med Chem. 2006. PMID: 16570913 Free PMC article.
Syntheses of tetrahydrofurobenzofurans and dihydromethanobenzodioxepines from 5-hydroxy-3-methyl-3H-benzofuran-2-one. Rearrangement and ring expansion under reductive conditions on treatment with hydrides.
Luo W, Yu QS, Holloway HW, Parrish D, Greig NH, Brossi A. Luo W, et al. Among authors: holloway hw. J Org Chem. 2005 Aug 5;70(16):6171-6. doi: 10.1021/jo0503052. J Org Chem. 2005. PMID: 16050674
GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease.
Li Y, Duffy KB, Ottinger MA, Ray B, Bailey JA, Holloway HW, Tweedie D, Perry T, Mattson MP, Kapogiannis D, Sambamurti K, Lahiri DK, Greig NH. Li Y, et al. Among authors: holloway hw. J Alzheimers Dis. 2010;19(4):1205-19. doi: 10.3233/JAD-2010-1314. J Alzheimers Dis. 2010. PMID: 20308787 Free PMC article.
Synthesis of the Alzheimer drug Posiphen into its primary metabolic products (+)-N1-norPosiphen, (+)-N8-norPosiphen and (+)-N1, N8-bisnorPosiphen, their inhibition of amyloid precursor protein, α-Synuclein synthesis, interleukin-1β release, and cholinergic action.
Yu QS, Reale M, Kamal MA, Holloway HW, Luo W, Sambamurti K, Ray B, Lahiri DK, Rogers JT, Greig NH. Yu QS, et al. Among authors: holloway hw. Antiinflamm Antiallergy Agents Med Chem. 2013;12(2):117-28. doi: 10.2174/1871523011312020003. Antiinflamm Antiallergy Agents Med Chem. 2013. PMID: 23360256 Free PMC article.
Preparation and Characterization of Tetrabenazine Enantiomers against Vesicular Monoamine Transporter 2.
Yu QS, Luo W, Deschamps J, Holloway HW, Kopajtic T, Katz JL, Brossi A, Greig NH. Yu QS, et al. Among authors: holloway hw. ACS Med Chem Lett. 2010 Mar 31;1(3):105-109. doi: 10.1021/ml1000189. ACS Med Chem Lett. 2010. PMID: 20694189 Free PMC article.
Thiothalidomides: novel isosteric analogues of thalidomide with enhanced TNF-alpha inhibitory activity.
Zhu X, Giordano T, Yu QS, Holloway HW, Perry TA, Lahiri DK, Brossi A, Greig NH. Zhu X, et al. Among authors: holloway hw. J Med Chem. 2003 Nov 20;46(24):5222-9. doi: 10.1021/jm030152f. J Med Chem. 2003. PMID: 14613324
Anticholinesterase activity of compounds related to geneserine tautomers. N-Oxides and 1,2-oxazines.
Yu QS, Zhu X, Holloway HW, Whittaker NF, Brossi A, Greig NH. Yu QS, et al. Among authors: holloway hw. J Med Chem. 2002 Aug 15;45(17):3684-91. doi: 10.1021/jm010491d. J Med Chem. 2002. PMID: 12166941
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