Holloway JW - Search Results

1

Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

Shrine N, Portelli MA, John C, Soler Artigas M, Bennett N, Hall R, Lewis J, Henry AP, Billington CK, Ahmad A, Packer RJ, Shaw D, Pogson ZEK, Fogarty A, McKeever TM, Singapuri A, Heaney LG, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Djukanovic R, Hankinson J, Niven R, Simpson A, Chung KF, Sterk PJ, Blakey JD, Adcock IM, Hu S, Guo Y, Obeidat M, Sin DD, van den Berge M, Nickle DC, Bossé Y, Tobin MD, Hall IP, Brightling CE, Wain LV, Sayers I. Shrine N, et al. Among authors: holloway jw. Lancet Respir Med. 2019 Jan;7(1):20-34. doi: 10.1016/S2213-2600(18)30389-8. Epub 2018 Dec 11. Lancet Respir Med. 2019. PMID: 30552067 Free PMC article.

2

Variant LTC(4) synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast.

Sampson AP, Siddiqui S, Buchanan D, Howarth PH, Holgate ST, Holloway JW, Sayers I. Sampson AP, et al. Among authors: holloway jw. Thorax. 2000 Oct;55 Suppl 2(Suppl 2):S28-31. doi: 10.1136/thorax.55.suppl_2.s28. Thorax. 2000. PMID: 10992553 Free PMC article. No abstract available.

3

A first trial of retrospective collaboration for positional cloning in complex inheritance: assay of the cytokine region on chromosome 5 by the consortium on asthma genetics (COAG).

Lonjou C, Barnes K, Chen H, Cookson WO, Deichmann KA, Hall IP, Holloway JW, Laitinen T, Palmer LJ, Wjst M, Morton NE. Lonjou C, et al. Among authors: holloway jw. Proc Natl Acad Sci U S A. 2000 Sep 26;97(20):10942-7. doi: 10.1073/pnas.97.20.10942. Proc Natl Acad Sci U S A. 2000. PMID: 11005866 Free PMC article. Clinical Trial.

4

Linkage analysis of the 5q31-33 candidate region for asthma in 240 UK families.

Holloway JW, Lonjou C, Beghé B, Peng Q, Gaunt TR, Gomes I, Hall IP, Dewar JC, Wilkinson J, Thomas NS, Holgate ST, Morton NE. Holloway JW, et al. Genes Immun. 2001 Feb;2(1):20-4. doi: 10.1038/sj.gene.6363723. Genes Immun. 2001. PMID: 11294563

5

Invited lecture: activation of the epithelial mesenchymal trophic unit in the pathogenesis of asthma.

Holgate ST, Lackie PM, Howarth PH, Roche WR, Puddicombe SM, Richter A, Wilson SJ, Holloway JW, Davies DE. Holgate ST, et al. Among authors: holloway jw. Int Arch Allergy Immunol. 2001 Jan-Mar;124(1-3):253-8. doi: 10.1159/000053726. Int Arch Allergy Immunol. 2001. PMID: 11306984

6

Allelic association and functional studies of promoter polymorphism in the leukotriene C4 synthase gene (LTC4S) in asthma.

Sayers I, Barton S, Rorke S, Beghé B, Hayward B, Van Eerdewegh P, Keith T, Clough JB, Ye S, Holloway JW, Sampson AP, Holgate ST. Sayers I, et al. Among authors: holloway jw. Thorax. 2003 May;58(5):417-24. doi: 10.1136/thorax.58.5.417. Thorax. 2003. PMID: 12728163 Free PMC article.

7

Promoter polymorphism in the 5-lipoxygenase (ALOX5) and 5-lipoxygenase-activating protein (ALOX5AP) genes and asthma susceptibility in a Caucasian population.

Sayers I, Barton S, Rorke S, Sawyer J, Peng Q, Beghé B, Ye S, Keith T, Clough JB, Holloway JW, Sampson AP, Holgate ST. Sayers I, et al. Among authors: holloway jw. Clin Exp Allergy. 2003 Aug;33(8):1103-10. doi: 10.1046/j.1365-2222.2003.01733.x. Clin Exp Allergy. 2003. PMID: 12911785

8

Polymorphisms in the interleukin-4 and interleukin-4 receptor alpha chain genes confer susceptibility to asthma and atopy in a Caucasian population.

Beghé B, Barton S, Rorke S, Peng Q, Sayers I, Gaunt T, Keith TP, Clough JB, Holgate ST, Holloway JW. Beghé B, et al. Among authors: holloway jw. Clin Exp Allergy. 2003 Aug;33(8):1111-7. doi: 10.1046/j.1365-2222.2003.01731.x. Clin Exp Allergy. 2003. PMID: 12911786

9

Polymorphisms in a disintegrin and metalloprotease 33 (ADAM33) predict impaired early-life lung function.

Simpson A, Maniatis N, Jury F, Cakebread JA, Lowe LA, Holgate ST, Woodcock A, Ollier WE, Collins A, Custovic A, Holloway JW, John SL. Simpson A, et al. Among authors: holloway jw. Am J Respir Crit Care Med. 2005 Jul 1;172(1):55-60. doi: 10.1164/rccm.200412-1708OC. Epub 2005 Apr 1. Am J Respir Crit Care Med. 2005. PMID: 15805180

10

Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities.

Holgate ST, Holloway J, Wilson S, Howarth PH, Haitchi HM, Babu S, Davies DE. Holgate ST, et al. J Allergy Clin Immunol. 2006 Mar;117(3):496-506; quiz 507. doi: 10.1016/j.jaci.2006.01.039. J Allergy Clin Immunol. 2006. PMID: 16522446 Review.

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