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PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer.
Kok M, Zwart W, Holm C, Fles R, Hauptmann M, Van't Veer LJ, Wessels LF, Neefjes J, Stål O, Linn SC, Landberg G, Michalides R. Kok M, et al. Among authors: holm c. Breast Cancer Res Treat. 2011 Jan;125(1):1-12. doi: 10.1007/s10549-010-0798-y. Epub 2010 Mar 9. Breast Cancer Res Treat. 2011. PMID: 20213082 Clinical Trial.
Extranuclear coactivator signaling confers insensitivity to tamoxifen.
Kumar R, Zhang H, Holm C, Vadlamudi RK, Landberg G, Rayala SK. Kumar R, et al. Among authors: holm c. Clin Cancer Res. 2009 Jun 15;15(12):4123-30. doi: 10.1158/1078-0432.CCR-08-2347. Epub 2009 May 26. Clin Cancer Res. 2009. PMID: 19470742 Free PMC article.
MTA1, a transcriptional activator of breast cancer amplified sequence 3.
Gururaj AE, Singh RR, Rayala SK, Holm C, den Hollander P, Zhang H, Balasenthil S, Talukder AH, Landberg G, Kumar R. Gururaj AE, et al. Among authors: holm c. Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6670-5. doi: 10.1073/pnas.0601989103. Epub 2006 Apr 14. Proc Natl Acad Sci U S A. 2006. PMID: 16617102 Free PMC article.
627 results