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[YB-1 as a potential target in cancer therapy].
Lage H, Surowiak P, Holm PS. Lage H, et al. Among authors: holm ps. Pathologe. 2008 Nov;29 Suppl 2:187-90. doi: 10.1007/s00292-008-1030-2. Pathologe. 2008. PMID: 18773210 Review. German.
Overcoming the classical multidrug resistance phenotype by adenoviral delivery of anti-MDR1 short hairpin RNAs and ribozymes.
Kaszubiak A, Holm PS, Lage H. Kaszubiak A, et al. Among authors: holm ps. Int J Oncol. 2007 Aug;31(2):419-30. Int J Oncol. 2007. PMID: 17611700
Regulation of MDR1 gene expression in multidrug-resistant cancer cells is independent from YB-1.
Kaszubiak A, Kupstat A, Müller U, Hausmann R, Holm PS, Lage H. Kaszubiak A, et al. Among authors: holm ps. Biochem Biophys Res Commun. 2007 May 25;357(1):295-301. doi: 10.1016/j.bbrc.2007.03.145. Epub 2007 Apr 2. Biochem Biophys Res Commun. 2007. PMID: 17418094
YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells.
Mantwill K, Naumann U, Seznec J, Girbinger V, Lage H, Surowiak P, Beier D, Mittelbronn M, Schlegel J, Holm PS. Mantwill K, et al. Among authors: holm ps. J Transl Med. 2013 Sep 18;11:216. doi: 10.1186/1479-5876-11-216. J Transl Med. 2013. PMID: 24044901 Free PMC article.
Impact of radiation therapy on the oncolytic adenovirus dl520: implications on the treatment of glioblastoma.
Bieler A, Mantwill K, Holzmüller R, Jürchott K, Kaszubiak A, Stärk S, Glockzin G, Lage H, Grosu AL, Gansbacher B, Holm PS. Bieler A, et al. Among authors: holm ps. Radiother Oncol. 2008 Mar;86(3):419-27. doi: 10.1016/j.radonc.2007.10.009. Epub 2007 Oct 29. Radiother Oncol. 2008. PMID: 17967494
YB-1 dependent virotherapy in combination with temozolomide as a multimodal therapy approach to eradicate malignant glioma.
Holzmüller R, Mantwill K, Haczek C, Rognoni E, Anton M, Kasajima A, Weichert W, Treue D, Lage H, Schuster T, Schlegel J, Gänsbacher B, Holm PS. Holzmüller R, et al. Among authors: holm ps. Int J Cancer. 2011 Sep 1;129(5):1265-76. doi: 10.1002/ijc.25783. Epub 2011 Jan 6. Int J Cancer. 2011. PMID: 21710499
Inhibition of the multidrug-resistant phenotype by targeting YB-1 with a conditionally oncolytic adenovirus: implications for combinatorial treatment regimen with chemotherapeutic agents.
Mantwill K, Köhler-Vargas N, Bernshausen A, Bieler A, Lage H, Kaszubiak A, Surowiak P, Dravits T, Treiber U, Hartung R, Gansbacher B, Holm PS. Mantwill K, et al. Among authors: holm ps. Cancer Res. 2006 Jul 15;66(14):7195-202. doi: 10.1158/0008-5472.CAN-05-2339. Cancer Res. 2006. PMID: 16849566
YB-1 relocates to the nucleus in adenovirus-infected cells and facilitates viral replication by inducing E2 gene expression through the E2 late promoter.
Holm PS, Bergmann S, Jurchott K, Lage H, Brand K, Ladhoff A, Mantwill K, Curiel DT, Dobbelstein M, Dietel M, Gansbacher B, Royer HD. Holm PS, et al. J Biol Chem. 2002 Mar 22;277(12):10427-34. doi: 10.1074/jbc.M106955200. Epub 2002 Jan 11. J Biol Chem. 2002. PMID: 11788582
Multidrug-resistant cancer cells facilitate E1-independent adenoviral replication: impact for cancer gene therapy.
Holm PS, Lage H, Bergmann S, Jürchott K, Glockzin G, Bernshausen A, Mantwill K, Ladhoff A, Wichert A, Mymryk JS, Ritter T, Dietel M, Gänsbacher B, Royer HD. Holm PS, et al. Cancer Res. 2004 Jan 1;64(1):322-8. doi: 10.1158/0008-5472.can-0482-2. Cancer Res. 2004. PMID: 14729641
Selection and characterization of a high-activity ribozyme directed against the antineoplastic drug resistance-associated ABC transporter BCRP/MXR/ABCG2.
Kowalski P, Wichert A, Holm PS, Dietel M, Lage H. Kowalski P, et al. Among authors: holm ps. Cancer Gene Ther. 2001 Mar;8(3):185-92. doi: 10.1038/sj.cgt.7700294. Cancer Gene Ther. 2001. PMID: 11332989
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