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Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49). UK Prospective Diabetes Study (UKPDS) Group.
Turner RC, Cull CA, Frighi V, Holman RR. Turner RC, et al. JAMA. 1999 Jun 2;281(21):2005-12. doi: 10.1001/jama.281.21.2005. JAMA. 1999. PMID: 10359389 Clinical Trial.
Modelling incremental benefits on complications rates when targeting lower HbA1c levels in people with Type 2 diabetes and cardiovascular disease.
Mostafa SA, Coleman RL, Agbaje OF, Gray AM, Holman RR, Bethel MA. Mostafa SA, et al. Diabet Med. 2018 Jan;35(1):72-77. doi: 10.1111/dme.13533. Epub 2017 Nov 16. Diabet Med. 2018. PMID: 29057545
Effect of metformin therapy on circulating amino acids in a randomized trial: the CAMERA study.
Preiss D, Rankin N, Welsh P, Holman RR, Kangas AJ, Soininen P, W├╝rtz P, Ala-Korpela M, Sattar N. Preiss D, et al. Diabet Med. 2016 Nov;33(11):1569-1574. doi: 10.1111/dme.13097. Epub 2016 Mar 3. Diabet Med. 2016. PMID: 26887663 Clinical Trial.
Participants' experiences of intensifying insulin therapy during the Treating to Target in Type 2 Diabetes (4-T) trial: qualitative interview study.
Jenkins N, Hallowell N, Farmer AJ, Holman RR, Lawton J. Jenkins N, et al. Diabet Med. 2011 May;28(5):543-8. doi: 10.1111/j.1464-5491.2010.03200.x. Diabet Med. 2011. PMID: 21480965 Clinical Trial.
Sulphonylurea failure in type 2 diabetes: treatment with a basal insulin supplement.
Holman RR, Steemson J, Turner RC. Holman RR, et al. Diabet Med. 1987 Sep-Oct;4(5):457-62. doi: 10.1111/j.1464-5491.1987.tb00909.x. Diabet Med. 1987. PMID: 2959438 Clinical Trial.
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