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Regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation.
Holness MJ, Sugden MC. Holness MJ, et al. Biochem Soc Trans. 2003 Dec;31(Pt 6):1143-51. doi: 10.1042/bst0311143. Biochem Soc Trans. 2003. PMID: 14641014 Review.
Acute and long-term nutrient-led modifications of gene expression: potential role of SIRT1 as a central co-ordinator of short and longer-term programming of tissue function.
Holness MJ, Caton PW, Sugden MC. Holness MJ, et al. Nutrition. 2010 May;26(5):491-501. doi: 10.1016/j.nut.2009.09.012. Epub 2010 Jan 25. Nutrition. 2010. PMID: 20097539 Review.
Control of cardiac pyruvate dehydrogenase activity in peroxisome proliferator-activated receptor-alpha transgenic mice.
Hopkins TA, Sugden MC, Holness MJ, Kozak R, Dyck JR, Lopaschuk GD. Hopkins TA, et al. Among authors: holness mj. Am J Physiol Heart Circ Physiol. 2003 Jul;285(1):H270-6. doi: 10.1152/ajpheart.00852.2002. Epub 2003 Mar 27. Am J Physiol Heart Circ Physiol. 2003. PMID: 12663261
Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs.
Sugden MC, Holness MJ. Sugden MC, et al. Among authors: holness mj. Am J Physiol Endocrinol Metab. 2003 May;284(5):E855-62. doi: 10.1152/ajpendo.00526.2002. Am J Physiol Endocrinol Metab. 2003. PMID: 12676647 Review.
Trials, tribulations and finally, a transporter: the identification of the mitochondrial pyruvate transporter.
Sugden MC, Holness MJ. Sugden MC, et al. Among authors: holness mj. Biochem J. 2003 Sep 15;374(Pt 3):e1-2. doi: 10.1042/bj20031105. Biochem J. 2003. PMID: 12954079 Free PMC article. Review.
Mechanisms underlying regulation of the expression and activities of the mammalian pyruvate dehydrogenase kinases.
Sugden MC, Holness MJ. Sugden MC, et al. Among authors: holness mj. Arch Physiol Biochem. 2006 Jul;112(3):139-49. doi: 10.1080/13813450600935263. Arch Physiol Biochem. 2006. PMID: 17132539 Review.
Damaging loss of self-control by stressed ╬▓-cells.
Holness MJ, Sugden MC. Holness MJ, et al. Diabetes. 2012 Feb;61(2):267-9. doi: 10.2337/db11-1647. Diabetes. 2012. PMID: 22275082 Free PMC article. No abstract available.
The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism: Going round in circles?
Sugden MC, Holness MJ. Sugden MC, et al. Among authors: holness mj. Islets. 2011 Nov-Dec;3(6):302-19. doi: 10.4161/isl.3.6.17806. Epub 2011 Nov 1. Islets. 2011. PMID: 21934355 Free PMC article. Review.
PPAR control: it's SIRTainly as easy as PGC.
Sugden MC, Caton PW, Holness MJ. Sugden MC, et al. Among authors: holness mj. J Endocrinol. 2010 Feb;204(2):93-104. doi: 10.1677/JOE-09-0359. Epub 2009 Sep 21. J Endocrinol. 2010. PMID: 19770177 Review.
Adipocyte pyruvate dehydrogenase kinase 4 expression is associated with augmented PPAR╬│ upregulation in early-life programming of later obesity.
Holness MJ, Zariwala G, Walker CG, Sugden MC. Holness MJ, et al. FEBS Open Bio. 2012 Mar 5;2:32-6. doi: 10.1016/j.fob.2012.02.003. Print 2012. FEBS Open Bio. 2012. PMID: 23650578 Free PMC article.
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