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Cancer drug resistance: an evolving paradigm.
Holohan C, Van Schaeybroeck S, Longley DB, Johnston PG. Holohan C, et al. Nat Rev Cancer. 2013 Oct;13(10):714-26. doi: 10.1038/nrc3599. Nat Rev Cancer. 2013. PMID: 24060863 Review.
Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP expression and HDAC inhibitor-induced apoptosis.
Kerr E, Holohan C, McLaughlin KM, Majkut J, Dolan S, Redmond K, Riley J, McLaughlin K, Stasik I, Crudden M, Van Schaeybroeck S, Fenning C, O'Connor R, Kiely P, Sgobba M, Haigh D, Johnston PG, Longley DB. Kerr E, et al. Among authors: holohan c. Cell Death Differ. 2012 Aug;19(8):1317-27. doi: 10.1038/cdd.2012.8. Epub 2012 Feb 10. Cell Death Differ. 2012. PMID: 22322857 Free PMC article.
Prognostic and therapeutic relevance of c-FLIP in acute myeloid leukaemia.
McLornan D, Hay J, McLaughlin K, Holohan C, Burnett AK, Hills RK, Johnston PG, Mills KI, McMullin MF, Longley DB, Gilkes A. McLornan D, et al. Among authors: holohan c. Br J Haematol. 2013 Jan;160(2):188-98. doi: 10.1111/bjh.12108. Epub 2012 Nov 20. Br J Haematol. 2013. PMID: 23167276
Prognostic and therapeutic relevance of FLIP and procaspase-8 overexpression in non-small cell lung cancer.
Riley JS, Hutchinson R, McArt DG, Crawford N, Holohan C, Paul I, Van Schaeybroeck S, Salto-Tellez M, Johnston PG, Fennell DA, Gately K, O'Byrne K, Cummins R, Kay E, Hamilton P, Stasik I, Longley DB. Riley JS, et al. Among authors: holohan c. Cell Death Dis. 2013 Dec 5;4(12):e951. doi: 10.1038/cddis.2013.481. Cell Death Dis. 2013. PMID: 24309938 Free PMC article.
FLIP: A Targetable Mediator of Resistance to Radiation in Non-Small Cell Lung Cancer.
McLaughlin KA, Nemeth Z, Bradley CA, Humphreys L, Stasik I, Fenning C, Majkut J, Higgins C, Crawford N, Holohan C, Johnston PG, Harrison T, Hanna GG, Butterworth KT, Prise KM, Longley DB. McLaughlin KA, et al. Among authors: holohan c. Mol Cancer Ther. 2016 Oct;15(10):2432-2441. doi: 10.1158/1535-7163.MCT-16-0211. Epub 2016 Jul 29. Mol Cancer Ther. 2016. PMID: 27474150 Free article.
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