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High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines.
Ketley A, Chen CZ, Li X, Arya S, Robinson TE, Granados-Riveron J, Udosen I, Morris GE, Holt I, Furling D, Chaouch S, Haworth B, Southall N, Shinn P, Zheng W, Austin CP, Hayes CJ, Brook JD. Ketley A, et al. Hum Mol Genet. 2014 Mar 15;23(6):1551-62. doi: 10.1093/hmg/ddt542. Epub 2013 Oct 30. Hum Mol Genet. 2014. PMID: 24179176 Free PMC article.
The accessory subunit of mitochondrial DNA polymerase gamma determines the DNA content of mitochondrial nucleoids in human cultured cells.
Di Re M, Sembongi H, He J, Reyes A, Yasukawa T, Martinsson P, Bailey LJ, Goffart S, Boyd-Kirkup JD, Wong TS, Fersht AR, Spelbrink JN, Holt IJ. Di Re M, et al. Among authors: holt ij. Nucleic Acids Res. 2009 Sep;37(17):5701-13. doi: 10.1093/nar/gkp614. Epub 2009 Jul 22. Nucleic Acids Res. 2009. PMID: 19625489 Free PMC article.
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