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Navigating the future of bacterial molecular epidemiology.
Baker S, Hanage WP, Holt KE. Baker S, et al. Among authors: holt ke. Curr Opin Microbiol. 2010 Oct;13(5):640-5. doi: 10.1016/j.mib.2010.08.002. Epub 2010 Sep 16. Curr Opin Microbiol. 2010. PMID: 20846899 Free PMC article. Review.
A linear plasmid truncation induces unidirectional flagellar phase change in H:z66 positive Salmonella Typhi.
Baker S, Holt K, Whitehead S, Goodhead I, Perkins T, Stocker B, Hardy J, Dougan G. Baker S, et al. Among authors: holt k. Mol Microbiol. 2007 Dec;66(5):1207-18. doi: 10.1111/j.1365-2958.2007.05995.x. Epub 2007 Nov 1. Mol Microbiol. 2007. PMID: 17976161 Free PMC article.
High-throughput genotyping of Salmonella enterica serovar Typhi allowing geographical assignment of haplotypes and pathotypes within an urban District of Jakarta, Indonesia.
Baker S, Holt K, van de Vosse E, Roumagnac P, Whitehead S, King E, Ewels P, Keniry A, Weill FX, Lightfoot D, van Dissel JT, Sanderson KE, Farrar J, Achtman M, Deloukas P, Dougan G. Baker S, et al. Among authors: holt k. J Clin Microbiol. 2008 May;46(5):1741-6. doi: 10.1128/JCM.02249-07. Epub 2008 Mar 5. J Clin Microbiol. 2008. PMID: 18322069 Free PMC article.
High-throughput sequencing provides insights into genome variation and evolution in Salmonella Typhi.
Holt KE, Parkhill J, Mazzoni CJ, Roumagnac P, Weill FX, Goodhead I, Rance R, Baker S, Maskell DJ, Wain J, Dolecek C, Achtman M, Dougan G. Holt KE, et al. Nat Genet. 2008 Aug;40(8):987-93. doi: 10.1038/ng.195. Epub 2008 Jul 27. Nat Genet. 2008. PMID: 18660809 Free PMC article.
Variation in Salmonella enterica serovar typhi IncHI1 plasmids during the global spread of resistant typhoid fever.
Phan MD, Kidgell C, Nair S, Holt KE, Turner AK, Hinds J, Butcher P, Cooke FJ, Thomson NR, Titball R, Bhutta ZA, Hasan R, Dougan G, Wain J. Phan MD, et al. Among authors: holt ke. Antimicrob Agents Chemother. 2009 Feb;53(2):716-27. doi: 10.1128/AAC.00645-08. Epub 2008 Nov 17. Antimicrob Agents Chemother. 2009. PMID: 19015365 Free PMC article.
Pseudogene accumulation in the evolutionary histories of Salmonella enterica serovars Paratyphi A and Typhi.
Holt KE, Thomson NR, Wain J, Langridge GC, Hasan R, Bhutta ZA, Quail MA, Norbertczak H, Walker D, Simmonds M, White B, Bason N, Mungall K, Dougan G, Parkhill J. Holt KE, et al. BMC Genomics. 2009 Jan 21;10:36. doi: 10.1186/1471-2164-10-36. BMC Genomics. 2009. PMID: 19159446 Free PMC article.
Detecting SNPs and estimating allele frequencies in clonal bacterial populations by sequencing pooled DNA.
Holt KE, Teo YY, Li H, Nair S, Dougan G, Wain J, Parkhill J. Holt KE, et al. Bioinformatics. 2009 Aug 15;25(16):2074-5. doi: 10.1093/bioinformatics/btp344. Epub 2009 Jun 3. Bioinformatics. 2009. PMID: 19497932 Free PMC article.
Typhoid in Kenya is associated with a dominant multidrug-resistant Salmonella enterica serovar Typhi haplotype that is also widespread in Southeast Asia.
Kariuki S, Revathi G, Kiiru J, Mengo DM, Mwituria J, Muyodi J, Munyalo A, Teo YY, Holt KE, Kingsley RA, Dougan G. Kariuki S, et al. Among authors: holt ke. J Clin Microbiol. 2010 Jun;48(6):2171-6. doi: 10.1128/JCM.01983-09. Epub 2010 Apr 14. J Clin Microbiol. 2010. PMID: 20392916 Free PMC article.
The sensitivity of real-time PCR amplification targeting invasive Salmonella serovars in biological specimens.
Nga TV, Karkey A, Dongol S, Thuy HN, Dunstan S, Holt K, Tu le TP, Campbell JI, Chau TT, Chau NV, Arjyal A, Koirala S, Basnyat B, Dolecek C, Farrar J, Baker S. Nga TV, et al. Among authors: holt k. BMC Infect Dis. 2010 May 21;10:125. doi: 10.1186/1471-2334-10-125. BMC Infect Dis. 2010. PMID: 20492644 Free PMC article.
High-throughput bacterial SNP typing identifies distinct clusters of Salmonella Typhi causing typhoid in Nepalese children.
Holt KE, Baker S, Dongol S, Basnyat B, Adhikari N, Thorson S, Pulickal AS, Song Y, Parkhill J, Farrar JJ, Murdoch DR, Kelly DF, Pollard AJ, Dougan G. Holt KE, et al. BMC Infect Dis. 2010 May 31;10:144. doi: 10.1186/1471-2334-10-144. BMC Infect Dis. 2010. PMID: 20509974 Free PMC article.
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