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Systemic hypothermia following spinal cord compression injury in the rat: axonal changes studied by beta-APP, ubiquitin, and PGP 9.5 immunohistochemistry.
Westergren H, Yu WR, Farooque M, Holtz A, Olsson Y. Westergren H, et al. Spinal Cord. 1999 Oct;37(10):696-704. doi: 10.1038/sj.sc.3100920. Spinal Cord. 1999. PMID: 10557125
The non-trauma group contained laminectomized animals submitted to a hypothermic procedure in which the core temperature was reduced from 38 to 30 degrees C. ...
The non-trauma group contained laminectomized animals submitted to a hypothermic procedure in which the core temperature was reduced …
Efficacy of the 21-aminosteroid U74006F in improving neurological recovery after spinal cord injury in rats.
Holtz A, Gerdin B. Holtz A, et al. Neurol Res. 1992 Mar;14(1):49-52. doi: 10.1080/01616412.1992.11740010. Neurol Res. 1992. PMID: 1351259
In these groups there was a similar improvement in neurological function and on day 9 the capacity angles were 49-55 degrees. In groups A and B, both of which received a bolus dose of U74006F at 1 hour, the neurological outcome improved on day one with capaci …
In these groups there was a similar improvement in neurological function and on day 9 the capacity angles were 49-55 degrees. In grou …
Exudation of fibronectin and albumin after spinal cord injury in rats.
Farooque M, Zhang Y, Holtz A, Olsson Y. Farooque M, et al. Acta Neuropathol. 1992;84(6):613-20. doi: 10.1007/BF00227738. Acta Neuropathol. 1992. PMID: 1471470
Such material was seen both proximal and distal to the primary injury and even in rats with a low magnitude of compression. Generally, with more severe trauma and longer survival periods extravascular albumin was more extensively distributed along the cord. ...
Such material was seen both proximal and distal to the primary injury and even in rats with a low magnitude of compression. Generally …
Blocking weight-induced spinal cord injury in rats: therapeutic effect of the 21-aminosteroid U74006F.
Holtz A, Gerdin B. Holtz A, et al. J Neurotrauma. 1991 Winter;8(4):239-45. doi: 10.1089/neu.1991.8.239. J Neurotrauma. 1991. PMID: 1803032
The effect of the 21-aminosteroid U74006F on neurologic recovery after a spinal cord compression trauma was investigated in rats. The compression was induced by a blocking weight technique, in which a 35 g (moderate injury) or a 50 g (severe injury) we …
The effect of the 21-aminosteroid U74006F on neurologic recovery after a spinal cord compression trauma was investigated in rats. The …
MK 801, an OBS N-methyl-D-aspartate channel blocker, does not improve the functional recovery nor spinal cord blood flow after spinal cord compression in rats.
Holtz A, Gerdin B. Holtz A, et al. Acta Neurol Scand. 1991 Oct;84(4):334-8. doi: 10.1111/j.1600-0404.1991.tb04964.x. Acta Neurol Scand. 1991. PMID: 1837648
To investigate whether N-methyl-D-aspartate (NMDA) receptor-mediated mechanisms are involved in the damage consequent to spinal cord injury, 20 rats were exposed to 5-min compression of the thoracic spinal cord produced with a load of 35 g on a 2.2 x 5 mm sized plat …
To investigate whether N-methyl-D-aspartate (NMDA) receptor-mediated mechanisms are involved in the damage consequent to spinal cord injury, …
[Time for intensive care of acute spinal cord injuries?].
Holtz A. Holtz A. Lakartidningen. 1991 Jul 10;88(28-29):2442-4. Lakartidningen. 1991. PMID: 1857170 Review. Swedish. No abstract available.
Effect of methylprednisolone on motor function and spinal cord blood flow after spinal cord compression in rats.
Holtz A, Nyström B, Gerdin B. Holtz A, et al. Acta Neurol Scand. 1990 Jul;82(1):68-73. doi: 10.1111/j.1600-0404.1990.tb01589.x. Acta Neurol Scand. 1990. PMID: 2239140
The effect of methylprednisolone (MP) on neurologic recovery and spinal cord blood flow (SCBF) was investigated up to 4 days after a spinal cord compression injury in rats. The injury was produced at midthoracic level by applying a load of 35 g on a 2.2 x 5.0 …
The effect of methylprednisolone (MP) on neurologic recovery and spinal cord blood flow (SCBF) was investigated up to 4 days after a
Neuropathological changes and neurological function after spinal cord compression in the rat.
Holtz A, Nyström B, Gerdin B, Olsson Y. Holtz A, et al. J Neurotrauma. 1990 Fall;7(3):155-67. doi: 10.1089/neu.1990.7.155. J Neurotrauma. 1990. PMID: 2258946
As part of a series of experimental investigations of the effects of various pharmacological agents on the outcome of compressive spinal cord trauma in the rat, the time course of the cell changes in the cord at the site of and distal to the compression was studied at the …
As part of a series of experimental investigations of the effects of various pharmacological agents on the outcome of compressive spi …
Relation between spinal cord blood flow and functional recovery after blocking weight-induced spinal cord injury in rats.
Holtz A, Nyström B, Gerdin B. Holtz A, et al. Neurosurgery. 1990 Jun;26(6):952-7. doi: 10.1097/00006123-199006000-00005. Neurosurgery. 1990. PMID: 2362673
Spinal cord blood flow (SCBF) and motor performance on the inclined plane were measured up to 9 days after a reversible spinal cord compression injury in 49 Sprague-Dawley rats. A load of 35 g on 11 mm2 of the thoracic spinal cord for 5 minutes caused transient para …
Spinal cord blood flow (SCBF) and motor performance on the inclined plane were measured up to 9 days after a reversible spinal cord c …
Blocking weight-induced spinal cord injury in rats: effects of TRH or naloxone on motor function recovery and spinal cord blood flow.
Holtz A, Nyström B, Gerdin B. Holtz A, et al. Acta Neurol Scand. 1989 Sep;80(3):215-20. doi: 10.1111/j.1600-0404.1989.tb03865.x. Acta Neurol Scand. 1989. PMID: 2508415
Spinal cord injury was induced by compression for 5 min with a load of 35 g on a 2.2 x 5.0 mm sized compression plate causing a transient paraparesis. ...Each drug was administered intravenously as a bolus dose of 2 mg/kg 60 min after injury followed b …
Spinal cord injury was induced by compression for 5 min with a load of 35 g on a 2.2 x 5.0 mm sized compression plate causing …
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