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Increased soluble amyloid-beta peptide and memory deficits in amyloid model mice overexpressing the low-density lipoprotein receptor-related protein.
Zerbinatti CV, Wozniak DF, Cirrito J, Cam JA, Osaka H, Bales KR, Zhuo M, Paul SM, Holtzman DM, Bu G. Zerbinatti CV, et al. Among authors: holtzman dm. Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):1075-80. doi: 10.1073/pnas.0305803101. Epub 2004 Jan 19. Proc Natl Acad Sci U S A. 2004. PMID: 14732699 Free PMC article.
P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model.
Cirrito JR, Deane R, Fagan AM, Spinner ML, Parsadanian M, Finn MB, Jiang H, Prior JL, Sagare A, Bales KR, Paul SM, Zlokovic BV, Piwnica-Worms D, Holtzman DM. Cirrito JR, et al. Among authors: holtzman dm. J Clin Invest. 2005 Nov;115(11):3285-90. doi: 10.1172/JCI25247. Epub 2005 Oct 20. J Clin Invest. 2005. PMID: 16239972 Free PMC article.
693 results