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Stevioside inhibits atherosclerosis by improving insulin signaling and antioxidant defense in obese insulin-resistant mice.
Geeraert B, Crombé F, Hulsmans M, Benhabilès N, Geuns JM, Holvoet P. Geeraert B, et al. Among authors: holvoet p. Int J Obes (Lond). 2010 Mar;34(3):569-77. doi: 10.1038/ijo.2009.261. Epub 2009 Dec 15. Int J Obes (Lond). 2010. PMID: 20010904
Oxidized lipoproteins in atherosclerosis and thrombosis.
Holvoet P, Collen D. Holvoet P, et al. FASEB J. 1994 Dec;8(15):1279-84. doi: 10.1096/fasebj.8.15.8001740. FASEB J. 1994. PMID: 8001740 Review.
Thrombosis and atherosclerosis.
Holvoet P, Collen D. Holvoet P, et al. Curr Opin Lipidol. 1997 Oct;8(5):320-8. doi: 10.1097/00041433-199710000-00012. Curr Opin Lipidol. 1997. PMID: 9335957 Review.
Intravascular fibrinolysis induced by tissue-type plasminogen activator or urokinase may contribute to the initiation of atherosclerosis by inducing P-selectin and platelet activating factor as well as to plaque rupture, either directly or indirectly, by activating metallo …
Intravascular fibrinolysis induced by tissue-type plasminogen activator or urokinase may contribute to the initiation of atherosclerosis by …
Oxidation of low density lipoproteins in the pathogenesis of atherosclerosis.
Holvoet P, Collen D. Holvoet P, et al. Atherosclerosis. 1998 Apr;137 Suppl:S33-8. doi: 10.1016/s0021-9150(97)00305-5. Atherosclerosis. 1998. PMID: 9694539 Review.
HDL-associated PAF-AH reduces endothelial adhesiveness in apoE-/- mice.
Theilmeier G, De Geest B, Van Veldhoven PP, Stengel D, Michiels C, Lox M, Landeloos M, Chapman MJ, Ninio E, Collen D, Himpens B, Holvoet P. Theilmeier G, et al. Among authors: holvoet p. FASEB J. 2000 Oct;14(13):2032-9. doi: 10.1096/fj.99-1029com. FASEB J. 2000. PMID: 11023987
Overexpression of human apolipoprotein AI in apoE-/- mice increased HDL levels 3-fold and reduced macrophage accumulation in an established assay of leukocyte homing to aortic root endothelium 3.2-fold (P<0.005). ...Adenoviral gene transfer of human PAF-acetylhydrolase …
Overexpression of human apolipoprotein AI in apoE-/- mice increased HDL levels 3-fold and reduced macrophage accumulation in an established …
Adenovirus-mediated gene transfer of human platelet-activating factor-acetylhydrolase prevents injury-induced neointima formation and reduces spontaneous atherosclerosis in apolipoprotein E-deficient mice.
Quarck R, De Geest B, Stengel D, Mertens A, Lox M, Theilmeier G, Michiels C, Raes M, Bult H, Collen D, Van Veldhoven P, Ninio E, Holvoet P. Quarck R, et al. Among authors: holvoet p. Circulation. 2001 May 22;103(20):2495-500. doi: 10.1161/01.cir.103.20.2495. Circulation. 2001. PMID: 11369691
PAF-AH gene transfer reduced oxidized lipoproteins by 82% (P<0.001), macrophages by 69% (P=0.006), and smooth muscle cells by 84% (P=0.002) in the arterial wall. ...Basal and PAF-AH activity after gene transfer were higher in male mice than in female mice …
PAF-AH gene transfer reduced oxidized lipoproteins by 82% (P<0.001), macrophages by 69% (P=0.006), and smooth muscle cells …
Oxidized LDL and HDL: antagonists in atherothrombosis.
Mertens A, Holvoet P. Mertens A, et al. Among authors: holvoet p. FASEB J. 2001 Oct;15(12):2073-84. doi: 10.1096/fj.01-0273rev. FASEB J. 2001. PMID: 11641234 Review.
Arg123-Tyr166 domain of human ApoA-I is critical for HDL-mediated inhibition of macrophage homing and early atherosclerosis in mice.
Holvoet P, Peeters K, Lund-Katz S, Mertens A, Verhamme P, Quarck R, Stengel D, Lox M, Deridder E, Bernar H, Nickel M, Theilmeier G, Ninio E, Phillips MC. Holvoet P, et al. Arterioscler Thromb Vasc Biol. 2001 Dec;21(12):1977-83. doi: 10.1161/hq1201.100221. Arterioscler Thromb Vasc Biol. 2001. PMID: 11742873
The macrophage-to-smooth muscle cell ratio of lesions was 2.1-fold higher in apo-I/apoA-II mice than in apoA-I mice (P<0.01). This was due to a 2.7-fold higher (P<0.001) in vivo macrophage homing in the aortic root of apoA-I/apoA-II mice. Plasma platelet-activ …
The macrophage-to-smooth muscle cell ratio of lesions was 2.1-fold higher in apo-I/apoA-II mice than in apoA-I mice (P<0.01). This …
Hypercholesterolemia in minipigs impairs left ventricular response to stress: association with decreased coronary flow reserve and reduced capillary density.
Theilmeier G, Verhamme P, Dymarkowski S, Beck H, Bernar H, Lox M, Janssens S, Herregods MC, Verbeken E, Collen D, Plate K, Flameng W, Holvoet P. Theilmeier G, et al. Among authors: holvoet p. Circulation. 2002 Aug 27;106(9):1140-6. doi: 10.1161/01.cir.0000026805.41747.54. Circulation. 2002. PMID: 12196342
In dobutamine stress test, cardiac output (P<0.05) and stroke volume (P<0.01) were lower in hypercholesterolemic pigs compared with controls. ...Hypercholesterolemia reduced endomyocardial coronary flow reserve (P<0.01) and capillary density (P
In dobutamine stress test, cardiac output (P<0.05) and stroke volume (P<0.01) were lower in hypercholesterolemic pigs co …
Dietary cholesterol withdrawal reduces vascular inflammation and induces coronary plaque stabilization in miniature pigs.
Verhamme P, Quarck R, Hao H, Knaapen M, Dymarkowski S, Bernar H, Van Cleemput J, Janssens S, Vermylen J, Gabbiani G, Kockx M, Holvoet P. Verhamme P, et al. Among authors: holvoet p. Cardiovasc Res. 2002 Oct;56(1):135-44. doi: 10.1016/s0008-6363(02)00515-1. Cardiovasc Res. 2002. PMID: 12237174
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