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Inhibition of cytochrome P450 3A4 by extracts and kavalactones of Piper methysticum (Kava-Kava).
Unger M, Holzgrabe U, Jacobsen W, Cummins C, Benet LZ. Unger M, et al. Among authors: holzgrabe u. Planta Med. 2002 Dec;68(12):1055-8. doi: 10.1055/s-2002-36360. Planta Med. 2002. PMID: 12494328
Random chemistry as a new tool for the generation of small compound libraries: development of a new acetylcholinesterase inhibitor.
Kapková P, Heller E, Unger M, Folkers G, Holzgrabe U. Kapková P, et al. Among authors: holzgrabe u. J Med Chem. 2005 Nov 17;48(23):7496-9. doi: 10.1021/jm058041z. J Med Chem. 2005. PMID: 16279811
Antileishmanial and cytotoxic compounds from Valeriana wallichii and identification of a novel nepetolactone derivative.
Glaser J, Schultheis M, Moll H, Hazra B, Holzgrabe U. Glaser J, et al. Among authors: holzgrabe u. Molecules. 2015 Apr 1;20(4):5740-53. doi: 10.3390/molecules20045740. Molecules. 2015. PMID: 25834987 Free PMC article.
Antileishmanial lead structures from nature: analysis of structure-activity relationships of a compound library derived from caffeic Acid bornyl ester.
Glaser J, Schultheis M, Hazra S, Hazra B, Moll H, Schurigt U, Holzgrabe U. Glaser J, et al. Among authors: holzgrabe u. Molecules. 2014 Jan 27;19(2):1394-410. doi: 10.3390/molecules19021394. Molecules. 2014. PMID: 24473204 Free PMC article.
Impurity profiling of N,N'-ethylenebis-l-cysteine diethyl ester (Bicisate).
Wahl O, Cleynhens J, Verbruggen AM, Holzgrabe U. Wahl O, et al. Among authors: holzgrabe u. J Pharm Biomed Anal. 2018 Feb 20;150:132-136. doi: 10.1016/j.jpba.2017.11.078. Epub 2017 Dec 5. J Pharm Biomed Anal. 2018. PMID: 29223061
Impurity profiling of L-methionine by HPLC on a mixed mode column.
Kühnreich R, Holzgrabe U. Kühnreich R, et al. Among authors: holzgrabe u. J Pharm Biomed Anal. 2016 Apr 15;122:118-25. doi: 10.1016/j.jpba.2016.01.057. Epub 2016 Feb 2. J Pharm Biomed Anal. 2016. PMID: 26852161
Why not using capillary electrophoresis in drug analysis?
Holzgrabe U, Brinz D, Kopec S, Weber C, Bitar Y. Holzgrabe U, et al. Electrophoresis. 2006 Jun;27(12):2283-92. doi: 10.1002/elps.200600016. Electrophoresis. 2006. PMID: 16786478 Review.
Capillary zone electrophoresis as a tool for the quality control of goldenseal extracts.
Unger M, Laug S, Holzgrabe U. Unger M, et al. Among authors: holzgrabe u. Electrophoresis. 2005 Jun;26(12):2430-6. doi: 10.1002/elps.200410322. Electrophoresis. 2005. PMID: 15912542
Isolation of a novel compound (MIMO2) from the methanolic extract of Moringa oleifera leaves: protective effects against vanadium-induced cytotoxity.
Igado OO, Glaser J, Ramos-Tirado M, Bankoğlu EE, Atiba FA, Holzgrabe U, Stopper H, Olopade JO. Igado OO, et al. Among authors: holzgrabe u. Drug Chem Toxicol. 2018 Jul;41(3):249-258. doi: 10.1080/01480545.2017.1366504. Epub 2017 Sep 19. Drug Chem Toxicol. 2018. PMID: 28925291
Fatty acid composition analysis in polysorbate 80 with high performance liquid chromatography coupled to charged aerosol detection.
Ilko D, Braun A, Germershaus O, Meinel L, Holzgrabe U. Ilko D, et al. Among authors: holzgrabe u. Eur J Pharm Biopharm. 2015 Aug;94:569-74. doi: 10.1016/j.ejpb.2014.11.018. Epub 2014 Nov 25. Eur J Pharm Biopharm. 2015. PMID: 25460583
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