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Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists.
Stahn C, Löwenberg M, Hommes DW, Buttgereit F. Stahn C, et al. Among authors: hommes dw. Mol Cell Endocrinol. 2007 Sep 15;275(1-2):71-8. doi: 10.1016/j.mce.2007.05.019. Epub 2007 Jun 2. Mol Cell Endocrinol. 2007. PMID: 17630118 Review.
Origin and functional activity of the membrane-bound glucocorticoid receptor.
Strehl C, Gaber T, Löwenberg M, Hommes DW, Verhaar AP, Schellmann S, Hahne M, Fangradt M, Wagegg M, Hoff P, Scheffold A, Spies CM, Burmester GR, Buttgereit F. Strehl C, et al. Among authors: hommes dw. Arthritis Rheum. 2011 Dec;63(12):3779-88. doi: 10.1002/art.30637. Arthritis Rheum. 2011. PMID: 21898343
Novel insights into mechanisms of glucocorticoid action and the development of new glucocorticoid receptor ligands.
Löwenberg M, Stahn C, Hommes DW, Buttgereit F. Löwenberg M, et al. Among authors: hommes dw. Steroids. 2008 Oct;73(9-10):1025-9. doi: 10.1016/j.steroids.2007.12.002. Epub 2007 Dec 14. Steroids. 2008. PMID: 18221974 Review.
Kinome analysis reveals nongenomic glucocorticoid receptor-dependent inhibition of insulin signaling.
Löwenberg M, Tuynman J, Scheffer M, Verhaar A, Vermeulen L, van Deventer S, Hommes D, Peppelenbosch M. Löwenberg M, et al. Among authors: hommes d. Endocrinology. 2006 Jul;147(7):3555-62. doi: 10.1210/en.2005-1602. Epub 2006 Mar 30. Endocrinology. 2006. PMID: 16574792
Glucocorticoid signaling: a nongenomic mechanism for T-cell immunosuppression.
Löwenberg M, Verhaar AP, van den Brink GR, Hommes DW. Löwenberg M, et al. Among authors: hommes dw. Trends Mol Med. 2007 Apr;13(4):158-63. doi: 10.1016/j.molmed.2007.02.001. Epub 2007 Feb 9. Trends Mol Med. 2007. PMID: 17293163 Review.
Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK.
Voorneveld PW, Kodach LL, Jacobs RJ, Liv N, Zonnevylle AC, Hoogenboom JP, Biemond I, Verspaget HW, Hommes DW, de Rooij K, van Noesel CJ, Morreau H, van Wezel T, Offerhaus GJ, van den Brink GR, Peppelenbosch MP, Ten Dijke P, Hardwick JC. Voorneveld PW, et al. Among authors: hommes dw. Gastroenterology. 2014 Jul;147(1):196-208.e13. doi: 10.1053/j.gastro.2014.03.052. Epub 2014 Apr 3. Gastroenterology. 2014. PMID: 24704720
Biological therapy in the management of recent-onset Crohn's disease: why, when and how?
Löwenberg M, Peppelenbosch M, Hommes D. Löwenberg M, et al. Among authors: hommes d. Drugs. 2006;66(11):1431-9. doi: 10.2165/00003495-200666110-00002. Drugs. 2006. PMID: 16906776 Review.
Rapid immunosuppressive effects of glucocorticoids mediated through Lck and Fyn.
Löwenberg M, Tuynman J, Bilderbeek J, Gaber T, Buttgereit F, van Deventer S, Peppelenbosch M, Hommes D. Löwenberg M, et al. Among authors: hommes d. Blood. 2005 Sep 1;106(5):1703-10. doi: 10.1182/blood-2004-12-4790. Epub 2005 May 17. Blood. 2005. PMID: 15899916
Specific inhibition of c-Raf activity by semapimod induces clinical remission in severe Crohn's disease.
Löwenberg M, Verhaar A, van den Blink B, ten Kate F, van Deventer S, Peppelenbosch M, Hommes D. Löwenberg M, et al. Among authors: hommes d. J Immunol. 2005 Aug 15;175(4):2293-300. doi: 10.4049/jimmunol.175.4.2293. J Immunol. 2005. PMID: 16081798
Regulatory macrophages induced by infliximab are involved in healing in vivo and in vitro.
Vos AC, Wildenberg ME, Arijs I, Duijvestein M, Verhaar AP, de Hertogh G, Vermeire S, Rutgeerts P, van den Brink GR, Hommes DW. Vos AC, et al. Among authors: hommes dw. Inflamm Bowel Dis. 2012 Mar;18(3):401-8. doi: 10.1002/ibd.21818. Epub 2011 Sep 20. Inflamm Bowel Dis. 2012. PMID: 21936028
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