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Hypercholesterolaemia, signs of islet microangiopathy and altered angiogenesis precede onset of type 2 diabetes in the Goto-Kakizaki (GK) rat.
Giroix MH, Irminger JC, Lacraz G, Noll C, Calderari S, Ehses JA, Coulaud J, Cornut M, Kassis N, Schmidlin F, Paul JL, Kergoat M, Janel N, Halban PA, Homo-Delarche F. Giroix MH, et al. Among authors: homo delarche f. Diabetologia. 2011 Sep;54(9):2451-62. doi: 10.1007/s00125-011-2223-4. Epub 2011 Jul 10. Diabetologia. 2011. PMID: 21744291
Islet endothelial activation and oxidative stress gene expression is reduced by IL-1Ra treatment in the type 2 diabetic GK rat.
Lacraz G, Giroix MH, Kassis N, Coulaud J, Galinier A, Noll C, Cornut M, Schmidlin F, Paul JL, Janel N, Irminger JC, Kergoat M, Portha B, Donath MY, Ehses JA, Homo-Delarche F. Lacraz G, et al. Among authors: homo delarche f. PLoS One. 2009 Sep 9;4(9):e6963. doi: 10.1371/journal.pone.0006963. PLoS One. 2009. PMID: 19742300 Free PMC article.
Islet structure and function in the GK rat.
Portha B, Lacraz G, Chavey A, Figeac F, Fradet M, Tourrel-Cuzin C, Homo-Delarche F, Giroix MH, Bailbé D, Gangnerau MN, Movassat J. Portha B, et al. Among authors: homo delarche f. Adv Exp Med Biol. 2010;654:479-500. doi: 10.1007/978-90-481-3271-3_21. Adv Exp Med Biol. 2010. PMID: 20217511 Review.
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