Hompesch M - Search Results

1

Pharmacokinetic and pharmacodynamic bioequivalence between regular human insulin (rDNA origin) in 0.9% sodium chloride ready-to-use infusion 1 U/mL and 100 U/mL concentrate diluted to 1 U/mL in healthy males.

Hompesch M, Hawryluk A, Hernandez M, Uchil B, Wilmington A, Peterson L. Hompesch M, et al. Diabetes Obes Metab. 2021 Dec;23(12):2679-2686. doi: 10.1111/dom.14520. Epub 2021 Sep 8. Diabetes Obes Metab. 2021. PMID: 34378307 Free PMC article. Clinical Trial.

2

Co-administration of liraglutide with insulin detemir demonstrates additive pharmacodynamic effects with no pharmacokinetic interaction.

Morrow L, Hompesch M, Guthrie H, Chang D, Chatterjee DJ. Morrow L, et al. Among authors: hompesch m. Diabetes Obes Metab. 2011 Jan;13(1):75-80. doi: 10.1111/j.1463-1326.2010.01322.x. Diabetes Obes Metab. 2011. PMID: 21114606

3

Accelerated insulin pharmacokinetics and improved postprandial glycemic control in patients with type 1 diabetes after coadministration of prandial insulins with hyaluronidase.

Hompesch M, Muchmore DB, Morrow L, Vaughn DE. Hompesch M, et al. Diabetes Care. 2011 Mar;34(3):666-8. doi: 10.2337/dc10-1892. Epub 2011 Jan 27. Diabetes Care. 2011. PMID: 21273493 Free PMC article. Clinical Trial.

4

Reduction in intrasubject variability in the pharmacokinetic response to insulin after subcutaneous co-administration with recombinant human hyaluronidase in healthy volunteers.

Morrow L, Muchmore DB, Ludington EA, Vaughn DE, Hompesch M. Morrow L, et al. Among authors: hompesch m. Diabetes Technol Ther. 2011 Oct;13(10):1039-45. doi: 10.1089/dia.2011.0115. Epub 2011 Jun 29. Diabetes Technol Ther. 2011. PMID: 21714645 Clinical Trial.

5

Safety, pharmacokinetics and pharmacodynamics of multiple-ascending doses of the novel glucokinase activator AZD1656 in patients with type 2 diabetes mellitus.

Morrow LA, Leonsson-Zachrisson M, Ericsson H, Wollbratt M, Knutsson M, Hompesch M, Norjavaara E. Morrow LA, et al. Among authors: hompesch m. Diabetes Obes Metab. 2012 Dec;14(12):1114-22. doi: 10.1111/j.1463-1326.2012.01661.x. Epub 2012 Jul 31. Diabetes Obes Metab. 2012. PMID: 22775976 Clinical Trial.

6

Comparative pharmacokinetics and insulin action for three rapid-acting insulin analogs injected subcutaneously with and without hyaluronidase.

Morrow L, Muchmore DB, Hompesch M, Ludington EA, Vaughn DE. Morrow L, et al. Among authors: hompesch m. Diabetes Care. 2013 Feb;36(2):273-5. doi: 10.2337/dc12-0808. Epub 2012 Oct 5. Diabetes Care. 2013. PMID: 23043164 Free PMC article. Clinical Trial.

7

Effect of exogenously administered glucagon versus spontaneous endogenous counter-regulation on glycaemic recovery from insulin-induced hypoglycaemia in patients with type 2 diabetes treated with a novel glucokinase activator, AZD1656, and metformin.

Krentz AJ, Morrow L, Petersson M, Norjavaara E, Hompesch M. Krentz AJ, et al. Among authors: hompesch m. Diabetes Obes Metab. 2014 Nov;16(11):1096-101. doi: 10.1111/dom.12323. Epub 2014 Jul 3. Diabetes Obes Metab. 2014. PMID: 24909093 Clinical Trial.

8

Albiglutide does not impair the counter-regulatory hormone response to hypoglycaemia: a randomized, double-blind, placebo-controlled, stepped glucose clamp study in subjects with type 2 diabetes mellitus.

Hompesch M, Jones-Leone A, Carr MC, Matthews J, Zhi H, Young M, Morrow L, Reinhardt RR. Hompesch M, et al. Diabetes Obes Metab. 2015 Jan;17(1):82-90. doi: 10.1111/dom.12398. Epub 2014 Oct 26. Diabetes Obes Metab. 2015. PMID: 25263215 Clinical Trial.

9

Glucodynamics of long-acting basal insulin peglispro compared with insulin glargine at steady state in patients with type 1 diabetes: substudy of a randomized crossover trial.

Morrow LA, Hompesch M, Jacober SJ, Leng Choi S, Qu Y, Sinha VP. Morrow LA, et al. Among authors: hompesch m. Diabetes Obes Metab. 2016 Nov;18(11):1065-1071. doi: 10.1111/dom.12691. Epub 2016 Jun 20. Diabetes Obes Metab. 2016. PMID: 27169522 Clinical Trial.

10

^LAPS Insulin115: A novel ultra-long-acting basal insulin with a unique action profile.

Wronkowitz N, Hartmann T, Görgens SW, Dietze-Schroeder D, Indrakusuma I, Choi IY, Park SH, Lee YM, Kwon SC, Kang Y, Hompesch M, Eckel J. Wronkowitz N, et al. Among authors: hompesch m. Diabetes Obes Metab. 2017 Dec;19(12):1722-1731. doi: 10.1111/dom.13006. Epub 2017 Jul 13. Diabetes Obes Metab. 2017. PMID: 28497570

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