Hon WC - Search Results

1

Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit.

Miled N, Yan Y, Hon WC, Perisic O, Zvelebil M, Inbar Y, Schneidman-Duhovny D, Wolfson HJ, Backer JM, Williams RL. Miled N, et al. Among authors: hon wc. Science. 2007 Jul 13;317(5835):239-42. doi: 10.1126/science.1135394. Science. 2007. PMID: 17626883

2

Form and flexibility in phosphoinositide 3-kinases.

Williams R, Berndt A, Miller S, Hon WC, Zhang X. Williams R, et al. Among authors: hon wc. Biochem Soc Trans. 2009 Aug;37(Pt 4):615-26. doi: 10.1042/BST0370615. Biochem Soc Trans. 2009. PMID: 19614567 Review.

3

The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors.

Berndt A, Miller S, Williams O, Le DD, Houseman BT, Pacold JI, Gorrec F, Hon WC, Liu Y, Rommel C, Gaillard P, Rückle T, Schwarz MK, Shokat KM, Shaw JP, Williams RL. Berndt A, et al. Among authors: hon wc. Nat Chem Biol. 2010 Feb;6(2):117-24. doi: 10.1038/nchembio.293. Nat Chem Biol. 2010. PMID: 20081827 Free PMC article.

4

The p110delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors.

Berndt A, Miller S, Williams O, Le DD, Houseman BT, Pacold JI, Gorrec F, Hon WC, Liu Y, Rommel C, Gaillard P, Rückle T, Schwarz MK, Shokat KM, Shaw JP, Williams RL. Berndt A, et al. Among authors: hon wc. Nat Chem Biol. 2010 Mar;6(3):244. doi: 10.1038/nchembio0310-244b. Nat Chem Biol. 2010. PMID: 20154668 No abstract available.

5

Molecular analysis of receptor protein tyrosine phosphatase mu-mediated cell adhesion.

Aricescu AR, Hon WC, Siebold C, Lu W, van der Merwe PA, Jones EY. Aricescu AR, et al. Among authors: hon wc. EMBO J. 2006 Feb 22;25(4):701-12. doi: 10.1038/sj.emboj.7600974. Epub 2006 Feb 2. EMBO J. 2006. PMID: 16456543 Free PMC article.

6

Cooperative recruitment of dynamin and BIN/amphiphysin/Rvs (BAR) domain-containing proteins leads to GTP-dependent membrane scission.

Meinecke M, Boucrot E, Camdere G, Hon WC, Mittal R, McMahon HT. Meinecke M, et al. Among authors: hon wc. J Biol Chem. 2013 Mar 1;288(9):6651-61. doi: 10.1074/jbc.M112.444869. Epub 2013 Jan 7. J Biol Chem. 2013. PMID: 23297414 Free PMC article.

7

The dynamics of signal triggering in a gp130-receptor complex.

Matadeen R, Hon WC, Heath JK, Jones EY, Fuller S. Matadeen R, et al. Among authors: hon wc. Structure. 2007 Apr;15(4):441-8. doi: 10.1016/j.str.2007.02.006. Structure. 2007. PMID: 17437716 Free PMC article.

8

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL.

Hon WC, Wilson MI, Harlos K, Claridge TD, Schofield CJ, Pugh CW, Maxwell PH, Ratcliffe PJ, Stuart DI, Jones EY. Hon WC, et al. Nature. 2002 Jun 27;417(6892):975-8. doi: 10.1038/nature00767. Epub 2002 Jun 5. Nature. 2002. PMID: 12050673

9

Structure of an enzyme required for aminoglycoside antibiotic resistance reveals homology to eukaryotic protein kinases.

Hon WC, McKay GA, Thompson PR, Sweet RM, Yang DS, Wright GD, Berghuis AM. Hon WC, et al. Cell. 1997 Jun 13;89(6):887-95. doi: 10.1016/s0092-8674(00)80274-3. Cell. 1997. PMID: 9200607 Free article.

10

Structural analyses of nucleotide binding to an aminoglycoside phosphotransferase.

Burk DL, Hon WC, Leung AK, Berghuis AM. Burk DL, et al. Among authors: hon wc. Biochemistry. 2001 Jul 31;40(30):8756-64. doi: 10.1021/bi010504p. Biochemistry. 2001. PMID: 11467935

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