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Essential role of IRF-3 in lipopolysaccharide-induced interferon-beta gene expression and endotoxin shock.
Sakaguchi S, Negishi H, Asagiri M, Nakajima C, Mizutani T, Takaoka A, Honda K, Taniguchi T. Sakaguchi S, et al. Biochem Biophys Res Commun. 2003 Jul 11;306(4):860-6. doi: 10.1016/s0006-291x(03)01049-0. Biochem Biophys Res Commun. 2003. PMID: 12821121
Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence.
Takaoka A, Hayakawa S, Yanai H, Stoiber D, Negishi H, Kikuchi H, Sasaki S, Imai K, Shibue T, Honda K, Taniguchi T. Takaoka A, et al. Nature. 2003 Jul 31;424(6948):516-23. doi: 10.1038/nature01850. Nature. 2003. PMID: 12872134
Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection.
Honda K, Sakaguchi S, Nakajima C, Watanabe A, Yanai H, Matsumoto M, Ohteki T, Kaisho T, Takaoka A, Akira S, Seya T, Taniguchi T. Honda K, et al. Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10872-7. doi: 10.1073/pnas.1934678100. Epub 2003 Sep 5. Proc Natl Acad Sci U S A. 2003. PMID: 12960379 Free PMC article.
Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling.
Honda K, Yanai H, Mizutani T, Negishi H, Shimada N, Suzuki N, Ohba Y, Takaoka A, Yeh WC, Taniguchi T. Honda K, et al. Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15416-21. doi: 10.1073/pnas.0406933101. Epub 2004 Oct 18. Proc Natl Acad Sci U S A. 2004. PMID: 15492225 Free PMC article.
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.
Takaoka A, Yanai H, Kondo S, Duncan G, Negishi H, Mizutani T, Kano S, Honda K, Ohba Y, Mak TW, Taniguchi T. Takaoka A, et al. Nature. 2005 Mar 10;434(7030):243-9. doi: 10.1038/nature03308. Epub 2005 Jan 23. Nature. 2005. PMID: 15665823
IRF-7 is the master regulator of type-I interferon-dependent immune responses.
Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T, Shimada N, Ohba Y, Takaoka A, Yoshida N, Taniguchi T. Honda K, et al. Nature. 2005 Apr 7;434(7034):772-7. doi: 10.1038/nature03464. Epub 2005 Mar 30. Nature. 2005. PMID: 15800576
Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction.
Honda K, Ohba Y, Yanai H, Negishi H, Mizutani T, Takaoka A, Taya C, Taniguchi T. Honda K, et al. Nature. 2005 Apr 21;434(7036):1035-40. doi: 10.1038/nature03547. Epub 2005 Apr 6. Nature. 2005. PMID: 15815647
This strategy also allows us to demonstrate endosomal activation of the IFN pathway by the otherwise inactive TLR9 ligand B/K-type oligodeoxynucleotide (CpG-B). ...
This strategy also allows us to demonstrate endosomal activation of the IFN pathway by the otherwise inactive TLR9 ligand B/K-type ol …
Wild-type measles virus infection in human CD46/CD150-transgenic mice: CD11c-positive dendritic cells establish systemic viral infection.
Shingai M, Inoue N, Okuno T, Okabe M, Akazawa T, Miyamoto Y, Ayata M, Honda K, Kurita-Taniguchi M, Matsumoto M, Ogura H, Taniguchi T, Seya T. Shingai M, et al. J Immunol. 2005 Sep 1;175(5):3252-61. doi: 10.4049/jimmunol.175.5.3252. J Immunol. 2005. PMID: 16116216
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