Honda T - Search Results

1

Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities.

Liby K, Honda T, Williams CR, Risingsong R, Royce DB, Suh N, Dinkova-Kostova AT, Stephenson KK, Talalay P, Sundararajan C, Gribble GW, Sporn MB. Liby K, et al. Among authors: honda t. Mol Cancer Ther. 2007 Jul;6(7):2113-9. doi: 10.1158/1535-7163.MCT-07-0180. Mol Cancer Ther. 2007. PMID: 17620440

2

Synthetic triterpenoids enhance transforming growth factor beta/Smad signaling.

Suh N, Roberts AB, Birkey Reffey S, Miyazono K, Itoh S, ten Dijke P, Heiss EH, Place AE, Risingsong R, Williams CR, Honda T, Gribble GW, Sporn MB. Suh N, et al. Among authors: honda t. Cancer Res. 2003 Mar 15;63(6):1371-6. Cancer Res. 2003. PMID: 12649201

3

The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo.

Place AE, Suh N, Williams CR, Risingsong R, Honda T, Honda Y, Gribble GW, Leesnitzer LM, Stimmel JB, Willson TM, Rosen E, Sporn MB. Place AE, et al. Among authors: honda y, honda t. Clin Cancer Res. 2003 Jul;9(7):2798-806. Clin Cancer Res. 2003. PMID: 12855660

4

The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling.

Liby K, Hock T, Yore MM, Suh N, Place AE, Risingsong R, Williams CR, Royce DB, Honda T, Honda Y, Gribble GW, Hill-Kapturczak N, Agarwal A, Sporn MB. Liby K, et al. Among authors: honda y, honda t. Cancer Res. 2005 Jun 1;65(11):4789-98. doi: 10.1158/0008-5472.CAN-04-4539. Cancer Res. 2005. PMID: 15930299

5

Design, synthesis, and anti-inflammatory activity both in vitro and in vivo of new betulinic acid analogues having an enone functionality in ring A.

Honda T, Liby KT, Su X, Sundararajan C, Honda Y, Suh N, Risingsong R, Williams CR, Royce DB, Sporn MB, Gribble GW. Honda T, et al. Among authors: honda y. Bioorg Med Chem Lett. 2006 Dec 15;16(24):6306-9. doi: 10.1016/j.bmcl.2006.09.012. Epub 2006 Sep 25. Bioorg Med Chem Lett. 2006. PMID: 16996735 Free PMC article.

6

The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-kappaB activation through direct inhibition of IkappaB kinase beta.

Yore MM, Liby KT, Honda T, Gribble GW, Sporn MB. Yore MM, et al. Among authors: honda t. Mol Cancer Ther. 2006 Dec;5(12):3232-9. doi: 10.1158/1535-7163.MCT-06-0444. Epub 2006 Dec 5. Mol Cancer Ther. 2006. PMID: 17148759

7

The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice.

Liby K, Royce DB, Williams CR, Risingsong R, Yore MM, Honda T, Gribble GW, Dmitrovsky E, Sporn TA, Sporn MB. Liby K, et al. Among authors: honda t. Cancer Res. 2007 Mar 15;67(6):2414-9. doi: 10.1158/0008-5472.CAN-06-4534. Cancer Res. 2007. PMID: 17363558

8

Novel tricyclic compounds having acetylene groups at C-8a and cyano enones in rings A and C: highly potent anti-inflammatory and cytoprotective agents.

Honda T, Sundararajan C, Yoshizawa H, Su X, Honda Y, Liby KT, Sporn MB, Gribble GW. Honda T, et al. Among authors: honda y. J Med Chem. 2007 Apr 19;50(8):1731-4. doi: 10.1021/jm070141c. Epub 2007 Mar 17. J Med Chem. 2007. PMID: 17367124 Free PMC article.

9

The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis.

Liby K, Black CC, Royce DB, Williams CR, Risingsong R, Yore MM, Liu X, Honda T, Gribble GW, Lamph WW, Sporn TA, Dmitrovsky E, Sporn MB. Liby K, et al. Among authors: honda t. Mol Cancer Ther. 2008 May;7(5):1251-7. doi: 10.1158/1535-7163.MCT-08-0023. Mol Cancer Ther. 2008. PMID: 18483313 Free PMC article.

10

A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin.

Liby K, Yore MM, Roebuck BD, Baumgartner KJ, Honda T, Sundararajan C, Yoshizawa H, Gribble GW, Williams CR, Risingsong R, Royce DB, Dinkova-Kostova AT, Stephenson KK, Egner PA, Yates MS, Groopman JD, Kensler TW, Sporn MB. Liby K, et al. Among authors: honda t. Cancer Res. 2008 Aug 15;68(16):6727-33. doi: 10.1158/0008-5472.CAN-08-1123. Cancer Res. 2008. PMID: 18701497 Free PMC article.

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