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Maintenance of IL-12-responsive CD4+ T cells during a Th2 response in Leishmania major-infected mice.
Hondowicz BD, Park AY, Elloso MM, Scott P. Hondowicz BD, et al. Eur J Immunol. 2000 Jul;30(7):2007-14. doi: 10.1002/1521-4141(200007)30:7<2007::AID-IMMU2007>3.0.CO;2-W. Eur J Immunol. 2000. PMID: 10940890
IL-2 is required for the generation of viral-specific CD4+ Th1 tissue-resident memory cells and B cells are essential for maintenance in the lung.
Hondowicz BD, Kim KS, Ruterbusch MJ, Keitany GJ, Pepper M. Hondowicz BD, et al. Eur J Immunol. 2018 Jan;48(1):80-86. doi: 10.1002/eji.201746928. Epub 2017 Oct 13. Eur J Immunol. 2018. PMID: 28948612 Free PMC article.
IL-12 is required to maintain a Th1 response during Leishmania major infection.
Park AY, Hondowicz BD, Scott P. Park AY, et al. Among authors: hondowicz bd. J Immunol. 2000 Jul 15;165(2):896-902. doi: 10.4049/jimmunol.165.2.896. J Immunol. 2000. PMID: 10878364
Regulation of the production of soluble IL-4 receptors in murine cutaneous leishmaniasis. The roles of IL-12 and IL-4.
Fernandez-Botran R, Chilton PM, Hondowicz BD, Vetvickova J, Yan J, Jones W 3rd, Scott P. Fernandez-Botran R, et al. Among authors: hondowicz bd. J Leukoc Biol. 1999 Sep;66(3):481-8. doi: 10.1002/jlb.66.3.481. J Leukoc Biol. 1999. PMID: 10496319
The role of IL-12 in the maintenance of an established Th1 immune response in experimental leishmaniasis.
Constantinescu CS, Hondowicz BD, Elloso MM, Wysocka M, Trinchieri G, Scott P. Constantinescu CS, et al. Among authors: hondowicz bd. Eur J Immunol. 1998 Jul;28(7):2227-33. doi: 10.1002/(SICI)1521-4141(199807)28:07<2227::AID-IMMU2227>3.0.CO;2-N. Eur J Immunol. 1998. PMID: 9692892
Infection with Leishmania major induces interleukin-12 production in vivo.
Vieira LQ, Hondowicz BD, Afonso LC, Wysocka M, Trinchieri G, Scott P. Vieira LQ, et al. Among authors: hondowicz bd. Immunol Lett. 1994 May;40(2):157-61. doi: 10.1016/0165-2478(94)90187-2. Immunol Lett. 1994. PMID: 7916331
Leishmania major-infected C3H mice treated with anti-IL-12 mAb develop but do not maintain a Th2 response.
Hondowicz BD, Scharton-Kersten TM, Jones DE, Scott P. Hondowicz BD, et al. J Immunol. 1997 Nov 15;159(10):5024-31. J Immunol. 1997. PMID: 9366430
ICOS expression by effector T cells influences the ability of regulatory T cells to inhibit anti-chromatin B cell responses in recipient mice.
Hondowicz BD, Batheja AO, Metzgar MH, Caton AJ, Erikson J. Hondowicz BD, et al. J Autoimmun. 2010 Jun;34(4):460-8. doi: 10.1016/j.jaut.2009.11.016. Epub 2009 Dec 22. J Autoimmun. 2010. PMID: 20022728 Free PMC article.
Efficient help for autoreactive B-cell activation requires CD4+ T-cell recognition of an agonist peptide at the effector stage.
Hondowicz BD, Batheja AO, Metzgar MH, Pagán AJ, Perng OA, Willms S, Caton AJ, Erikson J. Hondowicz BD, et al. Eur J Immunol. 2009 Sep;39(9):2377-82. doi: 10.1002/eji.200939471. Eur J Immunol. 2009. PMID: 19662636 Free PMC article.
Autoantibody production in lpr/lpr gld/gld mice reflects accumulation of CD4+ effector cells that are resistant to regulatory T cell activity.
Hondowicz BD, Fields ML, Nish SA, Larkin J, Caton AJ, Erikson J. Hondowicz BD, et al. J Autoimmun. 2008 Sep;31(2):98-109. doi: 10.1016/j.jaut.2008.04.022. Epub 2008 Jun 9. J Autoimmun. 2008. PMID: 18539433 Free PMC article.
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