Hong C - Search Results

1

Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells.

Sandhu J, Li S, Fairall L, Pfisterer SG, Gurnett JE, Xiao X, Weston TA, Vashi D, Ferrari A, Orozco JL, Hartman CL, Strugatsky D, Lee SD, He C, Hong C, Jiang H, Bentolila LA, Gatta AT, Levine TP, Ferng A, Lee R, Ford DA, Young SG, Ikonen E, Schwabe JWR, Tontonoz P. Sandhu J, et al. Among authors: hong c. Cell. 2018 Oct 4;175(2):514-529.e20. doi: 10.1016/j.cell.2018.08.033. Epub 2018 Sep 13. Cell. 2018. PMID: 30220461 Free PMC article.

2

LXRs regulate ER stress and inflammation through dynamic modulation of membrane phospholipid composition.

Rong X, Albert CJ, Hong C, Duerr MA, Chamberlain BT, Tarling EJ, Ito A, Gao J, Wang B, Edwards PA, Jung ME, Ford DA, Tontonoz P. Rong X, et al. Among authors: hong c. Cell Metab. 2013 Nov 5;18(5):685-97. doi: 10.1016/j.cmet.2013.10.002. Cell Metab. 2013. PMID: 24206663 Free PMC article.

3

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor.

Zhang L, Fairall L, Goult BT, Calkin AC, Hong C, Millard CJ, Tontonoz P, Schwabe JW. Zhang L, et al. Among authors: hong c. Genes Dev. 2011 Jun 15;25(12):1262-74. doi: 10.1101/gad.2056211. Genes Dev. 2011. PMID: 21685362 Free PMC article.

4

FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors.

Calkin AC, Goult BT, Zhang L, Fairall L, Hong C, Schwabe JW, Tontonoz P. Calkin AC, et al. Among authors: hong c. Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20107-12. doi: 10.1073/pnas.1111589108. Epub 2011 Nov 22. Proc Natl Acad Sci U S A. 2011. PMID: 22109552 Free PMC article.

5

IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure.

Rajbhandari P, Thomas BJ, Feng AC, Hong C, Wang J, Vergnes L, Sallam T, Wang B, Sandhu J, Seldin MM, Lusis AJ, Fong LG, Katz M, Lee R, Young SG, Reue K, Smale ST, Tontonoz P. Rajbhandari P, et al. Among authors: hong c. Cell. 2018 Jan 11;172(1-2):218-233.e17. doi: 10.1016/j.cell.2017.11.019. Epub 2017 Dec 14. Cell. 2018. PMID: 29249357 Free PMC article.

6

Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors.

Hong C, Tontonoz P. Hong C, et al. Curr Opin Genet Dev. 2008 Oct;18(5):461-7. doi: 10.1016/j.gde.2008.07.016. Epub 2008 Sep 7. Curr Opin Genet Dev. 2008. PMID: 18782619 Free PMC article. Review.

7

LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor.

Zelcer N, Hong C, Boyadjian R, Tontonoz P. Zelcer N, et al. Among authors: hong c. Science. 2009 Jul 3;325(5936):100-4. doi: 10.1126/science.1168974. Epub 2009 Jun 11. Science. 2009. PMID: 19520913 Free PMC article.

8

Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs.

Villanueva CJ, Vergnes L, Wang J, Drew BG, Hong C, Tu Y, Hu Y, Peng X, Xu F, Saez E, Wroblewski K, Hevener AL, Reue K, Fong LG, Young SG, Tontonoz P. Villanueva CJ, et al. Among authors: hong c. Cell Metab. 2013 Mar 5;17(3):423-35. doi: 10.1016/j.cmet.2013.01.016. Cell Metab. 2013. PMID: 23473036 Free PMC article.

9

Liver X receptors in lipid metabolism: opportunities for drug discovery.

Hong C, Tontonoz P. Hong C, et al. Nat Rev Drug Discov. 2014 Jun;13(6):433-44. doi: 10.1038/nrd4280. Epub 2014 May 16. Nat Rev Drug Discov. 2014. PMID: 24833295 Review.

10

The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice.

Hong C, Marshall SM, McDaniel AL, Graham M, Layne JD, Cai L, Scotti E, Boyadjian R, Kim J, Chamberlain BT, Tangirala RK, Jung ME, Fong L, Lee R, Young SG, Temel RE, Tontonoz P. Hong C, et al. Cell Metab. 2014 Nov 4;20(5):910-918. doi: 10.1016/j.cmet.2014.10.001. Epub 2014 Nov 4. Cell Metab. 2014. PMID: 25440061 Free PMC article.

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