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Year Number of Results
1991 1
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1999 3
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2002 1
2003 5
2004 4
2005 6
2006 7
2007 12
2008 18
2009 24
2010 23
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2012 32
2013 34
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2015 35
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635 results

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Page 1
Safety and Toxicology of Magnolol and Honokiol.
Sarrica A, Kirika N, Romeo M, Salmona M, Diomede L. Sarrica A, et al. Planta Med. 2018 Nov;84(16):1151-1164. doi: 10.1055/a-0642-1966. Epub 2018 Jun 20. Planta Med. 2018. PMID: 29925102 Free article. Review.
Magnolia officinalis and Magnolia obovata bark extracts have been used for thousands of years in Chinese and Japanese traditional medicines and are still widely employed as herbal preparations for their sedative, antioxidant, anti-inflammatory, antibiotic, and antis …
Magnolia officinalis and Magnolia obovata bark extracts have been used for thousands of years in Chinese and Japanese traditional medicines …
Natural Plants Compounds as Modulators of Epithelial-to-Mesenchymal Transition.
Avila-Carrasco L, Majano P, Sánchez-Toméro JA, Selgas R, López-Cabrera M, Aguilera A, González Mateo G. Avila-Carrasco L, et al. Front Pharmacol. 2019 Jul 30;10:715. doi: 10.3389/fphar.2019.00715. eCollection 2019. Front Pharmacol. 2019. PMID: 31417401 Free PMC article. Review.
Salvianolic acid-A and plumbagin block oxidative stress, while honokiol, gallic acid, piperlongumine, brusatol and paeoniflorin inhibit EMT transcription factors such as SNAIL, TWIST and ZEB. ...Additionally, this review highlights some relevant examples of clinical trials …
Salvianolic acid-A and plumbagin block oxidative stress, while honokiol, gallic acid, piperlongumine, brusatol and paeoniflorin inhib …
Reprogramming of Mitochondrial Respiratory Chain Complex by Targeting SIRT3-COX4I2 Axis Attenuates Osteoarthritis Progression.
Zhang Y, Liu Y, Hou M, Xia X, Liu J, Xu Y, Shi Q, Zhang Z, Wang L, Shen Y, Yang H, He F, Zhu X. Zhang Y, et al. Adv Sci (Weinh). 2023 Apr;10(10):e2206144. doi: 10.1002/advs.202206144. Epub 2023 Jan 22. Adv Sci (Weinh). 2023. PMID: 36683245 Free PMC article.
Silent mating type information regulation 2 homolog 3 (SIRT3) expression has a negative correlation with the severity of OA in both human arthritic cartilage and mice inflammatory chondrocytes. Global SIRT3 deletion accelerates pathological phenotype in post-traumatic OA m …
Silent mating type information regulation 2 homolog 3 (SIRT3) expression has a negative correlation with the severity of OA in both human ar …
Mitigation of honokiol on fluoride-induced mitochondrial oxidative stress, mitochondrial dysfunction, and cognitive deficits through activating AMPK/PGC-1alpha/Sirt3.
Wang D, Cao L, Zhou X, Wang G, Ma Y, Hao X, Fan H. Wang D, et al. J Hazard Mater. 2022 Sep 5;437:129381. doi: 10.1016/j.jhazmat.2022.129381. Epub 2022 Jun 16. J Hazard Mater. 2022. PMID: 35752048
The present study investigated the protective actions of honokiol on NaF-elicited cognitive deficits and elucidated the possible mechanism of honokiol-mediated protection. ...Further studies revealed that honokiol activated AMPK and upregulated the PGC-1alpha …
The present study investigated the protective actions of honokiol on NaF-elicited cognitive deficits and elucidated the possible mech …
SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes.
Chang Y, Wang C, Zhu J, Zheng S, Sun S, Wu Y, Jiang X, Li L, Ma R, Li G. Chang Y, et al. J Transl Med. 2023 Jul 22;21(1):494. doi: 10.1186/s12967-023-04246-9. J Transl Med. 2023. PMID: 37481555 Free PMC article.
Furthermore, we investigated the therapeutic effects of pharmacological activation of SIRT3 in diabetic mice via honokiol treatment, which exhibited similar effects to our genetic interventions. CONCLUSIONS: In summary, our findings suggest that SIRT3 ameliorates cognitive …
Furthermore, we investigated the therapeutic effects of pharmacological activation of SIRT3 in diabetic mice via honokiol treatment, …
Antidepressant-Like Effect and Mechanism of Action of Honokiol on the Mouse Lipopolysaccharide (LPS) Depression Model.
Zhang B, Wang PP, Hu KL, Li LN, Yu X, Lu Y, Chang HS. Zhang B, et al. Molecules. 2019 May 28;24(11):2035. doi: 10.3390/molecules24112035. Molecules. 2019. PMID: 31141940 Free PMC article.
Moreover, honokiol ameliorated LPS-induced NF-kappaB activation in the hippocampus and significantly reduced the levels of the pro-inflammatory cytokines; tumor necrosis factor alpha (TNF-alpha), interleukin 1beta (IL-1beta), and interferon gamma (IFN-gamma). ...In …
Moreover, honokiol ameliorated LPS-induced NF-kappaB activation in the hippocampus and significantly reduced the levels of the pro- …
Honokiol: An anticancer lignan.
Rauf A, Patel S, Imran M, Maalik A, Arshad MU, Saeed F, Mabkhot YN, Al-Showiman SS, Ahmad N, Elsharkawy E. Rauf A, et al. Biomed Pharmacother. 2018 Nov;107:555-562. doi: 10.1016/j.biopha.2018.08.054. Epub 2018 Aug 13. Biomed Pharmacother. 2018. PMID: 30114639 Review.
Honokiol has inhibitory role on the proliferation, invasion and survival of cancer cells in in vitro as well as in vivo studies. ...This review will shed light on the scopes and hurdles in the relevance of the bioactive lignan honokiol in cancer manage
Honokiol has inhibitory role on the proliferation, invasion and survival of cancer cells in in vitro as well as in vivo studie
Cancer Biomarkers for Integrative Oncology.
Ganguly A, Frank D, Kumar N, Cheng YC, Chu E. Ganguly A, et al. Curr Oncol Rep. 2019 Mar 5;21(4):32. doi: 10.1007/s11912-019-0782-6. Curr Oncol Rep. 2019. PMID: 30834992 Review.
PURPOSE OF REVIEW: There has been an increasing interest in using complementary and alternative medicine (CAM) approaches to treat cancer. It is therefore relevant and timely to determine if CAM biomarkers can be identified and developed to guide cancer diagnosis an …
PURPOSE OF REVIEW: There has been an increasing interest in using complementary and alternative medicine (CAM) approaches to treat cancer
Honokiol targets mitochondria to halt cancer progression and metastasis.
Pan J, Lee Y, Wang Y, You M. Pan J, et al. Mol Nutr Food Res. 2016 Jun;60(6):1383-95. doi: 10.1002/mnfr.201501007. Epub 2016 May 6. Mol Nutr Food Res. 2016. PMID: 27276215 Review.
Cancer continues to be the leading cause of death worldwide. Plants have a long history of use in the treatment of cancer. Honokiol (HNK) is an important bioactive compound found in the bark of Magnolia tree, and has been shown to inhibit cancer growth
Cancer continues to be the leading cause of death worldwide. Plants have a long history of use in the treatment of cancer.
Targeting cancer stem cells and signalling pathways through phytochemicals: A promising approach against colorectal cancer.
Liao W, Zhang L, Chen X, Xiang J, Zheng Q, Chen N, Zhao M, Zhang G, Xiao X, Zhou G, Zeng J, Tang J. Liao W, et al. Phytomedicine. 2023 Jan;108:154524. doi: 10.1016/j.phymed.2022.154524. Epub 2022 Oct 31. Phytomedicine. 2023. PMID: 36375238 Review.
BACKGROUND: Cancer stem cells (CSCs) are strongly associated with high tumourigenicity, chemotherapy or radiotherapy resistance, and metastasis and recurrence, particularly in colorectal cancer (CRC). ...Phytochemicals significantly inhibit self-renewal, migration, …
BACKGROUND: Cancer stem cells (CSCs) are strongly associated with high tumourigenicity, chemotherapy or radiotherapy resistance, and …
635 results