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Page 1
Mutation effects predicted from sequence co-variation.
Hopf TA, Ingraham JB, Poelwijk FJ, Schärfe CP, Springer M, Sander C, Marks DS. Hopf TA, et al. Nat Biotechnol. 2017 Feb;35(2):128-135. doi: 10.1038/nbt.3769. Epub 2017 Jan 16. Nat Biotechnol. 2017. PMID: 28092658 Free PMC article.
The EVcouplings Python framework for coevolutionary sequence analysis.
Hopf TA, Green AG, Schubert B, Mersmann S, Schärfe CPI, Ingraham JB, Toth-Petroczy A, Brock K, Riesselman AJ, Palmedo P, Kang C, Sheridan R, Draizen EJ, Dallago C, Sander C, Marks DS. Hopf TA, et al. Bioinformatics. 2019 May 1;35(9):1582-1584. doi: 10.1093/bioinformatics/bty862. Bioinformatics. 2019. PMID: 30304492 Free PMC article.
Structured States of Disordered Proteins from Genomic Sequences.
Toth-Petroczy A, Palmedo P, Ingraham J, Hopf TA, Berger B, Sander C, Marks DS. Toth-Petroczy A, et al. Among authors: hopf ta. Cell. 2016 Sep 22;167(1):158-170.e12. doi: 10.1016/j.cell.2016.09.010. Cell. 2016. PMID: 27662088 Free PMC article.
Deep generative modeling of the human proteome reveals over a hundred novel genes involved in rare genetic disorders.
Orenbuch R, Kollasch AW, Spinner HD, Shearer CA, Hopf TA, Franceschi D, Dias M, Frazer J, Marks DS. Orenbuch R, et al. Among authors: hopf ta. Res Sq [Preprint]. 2024 Jan 4:rs.3.rs-3740259. doi: 10.21203/rs.3.rs-3740259/v1. Res Sq. 2024. Update in: Nat Genet. 2025 Dec;57(12):3165-3174. doi: 10.1038/s41588-025-02400-1. PMID: 38260496 Free PMC article. Updated. Preprint.
18 results