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Molecular mechanisms of the preventable causes of cancer in the United States.
Golemis EA, Scheet P, Beck TN, Scolnick EM, Hunter DJ, Hawk E, Hopkins N. Golemis EA, et al. Genes Dev. 2018 Jul 1;32(13-14):868-902. doi: 10.1101/gad.314849.118. Epub 2018 Jun 26. Genes Dev. 2018. PMID: 29945886 Free PMC article. Review.
Inactivation of serine protease Matriptase1a by its inhibitor Hai1 is required for epithelial integrity of the zebrafish epidermis.
Carney TJ, von der Hardt S, Sonntag C, Amsterdam A, Topczewski J, Hopkins N, Hammerschmidt M. Carney TJ, et al. Development. 2007 Oct;134(19):3461-71. doi: 10.1242/dev.004556. Epub 2007 Aug 29. Development. 2007. PMID: 17728346
A zebrafish sox9 gene required for cartilage morphogenesis.
Yan YL, Miller CT, Nissen RM, Singer A, Liu D, Kirn A, Draper B, Willoughby J, Morcos PA, Amsterdam A, Chung BC, Westerfield M, Haffter P, Hopkins N, Kimmel C, Postlethwait JH. Yan YL, et al. Development. 2002 Nov;129(21):5065-79. Development. 2002. PMID: 12397114
Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers.
Zhang G, Hoersch S, Amsterdam A, Whittaker CA, Lees JA, Hopkins N. Zhang G, et al. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16940-5. doi: 10.1073/pnas.1011548107. Epub 2010 Sep 13. Proc Natl Acad Sci U S A. 2010. PMID: 20837522 Free PMC article.
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator.
Sansam CL, Cruz NM, Danielian PS, Amsterdam A, Lau ML, Hopkins N, Lees JA. Sansam CL, et al. Genes Dev. 2010 Jan 15;24(2):183-94. doi: 10.1101/gad.1860310. Genes Dev. 2010. PMID: 20080954 Free PMC article.
Zebrafish Hagoromo mutants up-regulate fgf8 postembryonically and develop neuroblastoma.
Amsterdam A, Lai K, Komisarczuk AZ, Becker TS, Bronson RT, Hopkins N, Lees JA. Amsterdam A, et al. Mol Cancer Res. 2009 Jun;7(6):841-50. doi: 10.1158/1541-7786.MCR-08-0555. Epub 2009 Jun 16. Mol Cancer Res. 2009. PMID: 19531571 Free PMC article.
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