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1938 1
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128 results

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Hordenine Activated Dermal Papilla Cells and Promoted Hair Regrowth by Activating Wnt Signaling Pathway.
Wang C, Zang K, Tang Z, Yang T, Ye X, Dang Y. Wang C, et al. Nutrients. 2023 Jan 30;15(3):694. doi: 10.3390/nu15030694. Nutrients. 2023. PMID: 36771401 Free PMC article.
Hordenine is effective in treating hyperpigmentation, fighting diabetes and resisting fibrosis and acute inflammation. However, the role of Hordenine on hair growth has not been elucidated. Here, we found that Hordenine treatments significantly enhance prolif
Hordenine is effective in treating hyperpigmentation, fighting diabetes and resisting fibrosis and acute inflammation. However, the r
Beneficial Effects of Hordenine on a Model of Ulcerative Colitis.
Xu Z, Zhang Q, Ding C, Wen F, Sun F, Liu Y, Tao C, Yao J. Xu Z, et al. Molecules. 2023 Mar 21;28(6):2834. doi: 10.3390/molecules28062834. Molecules. 2023. PMID: 36985809 Free PMC article.
However, the efficacy and underlying mechanisms of hordenine in treating ulcerative colitis (UC) remain unclear. To address this, we examined the therapeutic effects of hordenine on dextran sodium sulphate (DSS)-induced UC by comparing disease activity index (DAI), …
However, the efficacy and underlying mechanisms of hordenine in treating ulcerative colitis (UC) remain unclear. To address this, we …
The beer component hordenine inhibits alcohol addiction-associated behaviours in mice.
Li Y, Vogel C, Kalinichenko LS, Hübner H, Weikert D, Schaefer N, Gmeiner P, Villmann C, Pischetsrieder M, Müller CP. Li Y, et al. Addict Biol. 2023 Aug;28(8):e13305. doi: 10.1111/adb.13305. Addict Biol. 2023. PMID: 37500485
However, it independently enhanced alcohol CPP retrieval. Hordenine had a dose-dependent inhibitory effect on locomotor activity. Chronic hordenine exposure enhanced monoamine tissue levels in many brain regions. ...
However, it independently enhanced alcohol CPP retrieval. Hordenine had a dose-dependent inhibitory effect on locomotor activity. Chr …
Permeability of dopamine D2 receptor agonist hordenine across the intestinal and blood-brain barrier in vitro.
Hahn M, Lindemann V, Behrens M, Mulac D, Langer K, Esselen M, Humpf HU. Hahn M, et al. PLoS One. 2022 Jun 16;17(6):e0269486. doi: 10.1371/journal.pone.0269486. eCollection 2022. PLoS One. 2022. PMID: 35709159 Free PMC article.
Since the pharmacokinetic profile of hordenine has been described to a limited extent, the present study focused on the transfer and transport of hordenine across the intestinal epithelium and the blood-brain barrier (BBB) in vitro. ...To determine the biotransforma …
Since the pharmacokinetic profile of hordenine has been described to a limited extent, the present study focused on the transfer and …
Quorum sensing inhibition of hordenine analogs on Pseudomonas aeruginosa and Serratia marcescens.
Liu Y, Li JJ, Li HY, Deng SM, Jia AQ. Liu Y, et al. Synth Syst Biotechnol. 2021 Nov 1;6(4):360-368. doi: 10.1016/j.synbio.2021.09.010. eCollection 2021 Dec. Synth Syst Biotechnol. 2021. PMID: 34786511 Free PMC article.
In this work, we tested the QS inhibitory potential of 27 hordenine analogs against QS and biofilm formation in P. aeruginosa and S. marcescens. ...Four analogs (7, 28, 2, and 12) showed QS inhibitory activity against S. marcescens, two of which (7 and 28) demonstrated bet …
In this work, we tested the QS inhibitory potential of 27 hordenine analogs against QS and biofilm formation in P. aeruginosa and S. …
Hordenine: A Novel Quorum Sensing Inhibitor and Antibiofilm Agent against Pseudomonas aeruginosa.
Zhou JW, Luo HZ, Jiang H, Jian TK, Chen ZQ, Jia AQ. Zhou JW, et al. J Agric Food Chem. 2018 Feb 21;66(7):1620-1628. doi: 10.1021/acs.jafc.7b05035. Epub 2018 Feb 8. J Agric Food Chem. 2018. PMID: 29353476
The quorum sensing (QS) inhibitory activity of hordenine from sprouting barley against foodborne pathogen Pseudomonas aeruginosa was evaluated for the first time here. ...Hordenine treatment inhibited the production of QS-related extracellular virulence factors of P …
The quorum sensing (QS) inhibitory activity of hordenine from sprouting barley against foodborne pathogen Pseudomonas aeruginosa was …
Metabolomic analysis of quorum sensing inhibitor hordenine on Pseudomonas aeruginosa.
Zhou JW, Muhammad J, Sun B, Yang R, Wadood A, Wang JS, Jia AQ. Zhou JW, et al. Appl Microbiol Biotechnol. 2019 Aug;103(15):6271-6285. doi: 10.1007/s00253-019-09878-w. Epub 2019 Jun 3. Appl Microbiol Biotechnol. 2019. PMID: 31161392
Proton magnetic resonance-based metabolomics analysis was performed to determine the global metabolite changes in pathogenic bacterium Pseudomonas aeruginosa PAO1 following exposure to quorum sensing (QS) inhibitor hordenine. Pyocyanin inhibition assay confirmed that ho
Proton magnetic resonance-based metabolomics analysis was performed to determine the global metabolite changes in pathogenic bacterium Pseud …
Unauthorized ingredients in "nootropic" dietary supplements: A review of the history, pharmacology, prevalence, international regulations, and potential as doping agents.
Jędrejko K, Catlin O, Stewart T, Anderson A, Muszyńska B, Catlin DH. Jędrejko K, et al. Drug Test Anal. 2023 Aug;15(8):803-839. doi: 10.1002/dta.3529. Epub 2023 Jun 25. Drug Test Anal. 2023. PMID: 37357012 Review.
Prohibited stimulants or ss2-agonists commonly used in "pre-workout," "weight loss," or "thermogenic" DS such as octodrine, hordenine, or higenamine are often stacked with nootropic substances. ...
Prohibited stimulants or ss2-agonists commonly used in "pre-workout," "weight loss," or "thermogenic" DS such as octodrine, hordenine
Quantification of hordenine in a complex plant matrix by direct analysis in real time-high-resolution mass spectrometry: Application to the "plant of concern" Sceletium tortuosum.
Appley MG, Chambers MI, Musah RA. Appley MG, et al. Drug Test Anal. 2022 Apr;14(4):604-612. doi: 10.1002/dta.3193. Epub 2021 Nov 24. Drug Test Anal. 2022. PMID: 34750996
By this method, the lower limit of quantification (LLOQ) was found to be 1 mug/ml. Observed hordenine concentrations ranged from 0.02738 to 1.071 mg of hordenine per gram of plant material. The developed technique provides an effective and quick means for the detect …
By this method, the lower limit of quantification (LLOQ) was found to be 1 mug/ml. Observed hordenine concentrations ranged from 0.02 …
Hordenine: pharmacology, pharmacokinetics and behavioural effects in the horse.
Frank M, Weckman TJ, Wood T, Woods WE, Tai CL, Chang SL, Ewing A, Blake JW, Tobin T. Frank M, et al. Equine Vet J. 1990 Nov;22(6):437-41. doi: 10.1111/j.2042-3306.1990.tb04312.x. Equine Vet J. 1990. PMID: 2269269
Hordenine is an alkaloid occurring naturally in grains, sprouting barley, and certain grasses. ...Treated horses were tested in a variable interval responding apparatus 30 mins after dosing and no residual stimulation or depressant effects of hordenine were apparent
Hordenine is an alkaloid occurring naturally in grains, sprouting barley, and certain grasses. ...Treated horses were tested in a var
128 results