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Vitamin C levels in blood are influenced by polymorphisms in glutathione S-transferases.
Horska A, Mislanova C, Bonassi S, Ceppi M, Volkovova K, Dusinska M. Horska A, et al. Eur J Nutr. 2011 Sep;50(6):437-46. doi: 10.1007/s00394-010-0147-2. Epub 2010 Dec 9. Eur J Nutr. 2011. PMID: 21152927
CONCLUSIONS: The correspondence of lower vitamin C levels with non-functional GST isoenzymes may indicate a causal connection between two antioxidant defence pathways, also the underlying mechanism is not yet clear. ...
CONCLUSIONS: The correspondence of lower vitamin C levels with non-functional GST isoenzymes may indicate a causal connection between …
Genetic predisposition and health effect of occupational exposure to asbestos.
Horská A, Kazimírová A, Barancoková M, Wsólová L, Tulinská J, Dusinská M. Horská A, et al. Neuro Endocrinol Lett. 2006 Dec;27 Suppl 2:100-3. Neuro Endocrinol Lett. 2006. PMID: 17159790
OBJECTIVES: As asbestos presents a direct genetic hazard for humans, a small-scale molecular epidemiological study was conducted to monitor 61 subjects long-term exposed to asbestos in comparison with 49 town controls and 21 control subjects from administration of t …
OBJECTIVES: As asbestos presents a direct genetic hazard for humans, a small-scale molecular epidemiological study was conduct …
Genetic determinants of quantitative traits associated with cardiovascular disease risk.
Smolková B, Bonassi S, Buociková V, Dušinská M, Horská A, Kuba D, Džupinková Z, Rašlová K, Gašparovič J, Slíž I, Ceppi M, Vohnout B, Wsólová L, Volkovová K. Smolková B, et al. Among authors: horska a. Mutat Res. 2015 Aug;778:18-25. doi: 10.1016/j.mrfmmm.2015.05.005. Epub 2015 May 15. Mutat Res. 2015. PMID: 26043189
Does occupational exposure to mineral fibres cause DNA or chromosome damage?
Dusinská M, Barancoková M, Kazimírová A, Harrington V, Volkovová K, Staruchová M, Horská A, Wsólová L, Collins A. Dusinská M, et al. Mutat Res. 2004 Sep 3;553(1-2):103-10. doi: 10.1016/j.mrfmmm.2004.06.029. Mutat Res. 2004. PMID: 15288537
Markers of genetic stability were monitored in lymphocytes from 98 workers employed in rockwool manufacture in a factory in the Slovak Republic, and 43 controls (administrative employees in the same factory). ...
Markers of genetic stability were monitored in lymphocytes from 98 workers employed in rockwool manufacture in a factory in the Slova …
Genotoxic effects of asbestos in humans.
Dusinská M, Collins A, Kazimírová A, Barancoková M, Harrington V, Volkovová K, Staruchová M, Horská A, Wsólová L, Kocan A, Petrík J, Machata M, Ratcliffe B, Kyrtopoulos S. Dusinská M, et al. Mutat Res. 2004 Sep 3;553(1-2):91-102. doi: 10.1016/j.mrfmmm.2004.06.027. Mutat Res. 2004. PMID: 15288536
The present molecular epidemiological study was conducted in a former asbestos cement plant in Slovakia. Altogether 82 subjects were investigated, 61 exposed subjects (24 smokers and 37 non-smokers), and 21 factory controls (8 smokers and 13 non-smokers). ...Though the exp …
The present molecular epidemiological study was conducted in a former asbestos cement plant in Slovakia. Altogether 82 subjects were …
Folate levels determine effect of antioxidant supplementation on micronuclei in subjects with cardiovascular risk.
Smolková B, Dusinská M, Raslová K, Barancoková M, Kazimírová A, Horská A, Spustová V, Collins A. Smolková B, et al. Mutagenesis. 2004 Nov;19(6):469-76. doi: 10.1093/mutage/geh059. Mutagenesis. 2004. PMID: 15548759 Clinical Trial.

In antioxidant-supplemented myocardial infarction survivors we found an increase in the ferric reducing ability of plasma (P < 0.001) and a decrease in malondialdehyde (P = 0.001). Micronucleus frequency showed a decrease, strongest in subjects with normal folate

In antioxidant-supplemented myocardial infarction survivors we found an increase in the ferric reducing ability of plasma (P < 0.001) and

Glutathione S-transferase polymorphisms influence the level of oxidative DNA damage and antioxidant protection in humans.
Dusinská M, Ficek A, Horská A, Raslová K, Petrovská H, Vallová B, Drlicková M, Wood SG, Stupáková A, Gasparovic J, Bobek P, Nagyová A, Kováciková Z, Blazícek P, Liegebel U, Collins AR. Dusinská M, et al. Mutat Res. 2001 Oct 1;482(1-2):47-55. doi: 10.1016/s0027-5107(01)00209-3. Mutat Res. 2001. PMID: 11535248
The homozygous GSTP1 a/a genotype was associated with significantly higher levels of GST activity measured in lymphocytes, in comparison with the b/b genotype. ...
The homozygous GSTP1 a/a genotype was associated with significantly higher levels of GST activity measured in lymphocytes, in …
Antioxidant supplementation reduces inter-individual variation in markers of oxidative damage.
Volkovová K, Barancoková M, Kazimírová A, Collins A, Raslová K, Smolková B, Horská A, Wsólová L, Dusinská M. Volkovová K, et al. Free Radic Res. 2005 Jun;39(6):659-66. doi: 10.1080/10715760500117472. Free Radic Res. 2005. PMID: 16036344 Clinical Trial.
Antioxidant supplementation significantly increased the levels of vitamin C, ss-carotene, a-tocopherol and selenium in plasma. ...These results indicate that a combined antioxidant supplementation (a) is effective even at very moderate doses; (b) significantl …
Antioxidant supplementation significantly increased the levels of vitamin C, ss-carotene, a-tocopherol and selenium in plasma. ...The …
Are glutathione S transferases involved in DNA damage signalling? Interactions with DNA damage and repair revealed from molecular epidemiology studies.
Dusinska M, Staruchova M, Horska A, Smolkova B, Collins A, Bonassi S, Volkovova K. Dusinska M, et al. Mutat Res. 2012 Aug 1;736(1-2):130-7. doi: 10.1016/j.mrfmmm.2012.03.003. Epub 2012 Mar 20. Mutat Res. 2012. PMID: 22450146
Glutathione S-transferases (GSTs) are members of a multigene family of isoenzymes that are important in the control of oxidative stress and in phase II metabolism. ...Using a molecular epidemiology approach, we have investigated a potential involvement of GST …
Glutathione S-transferases (GSTs) are members of a multigene family of isoenzymes that are important in the control of oxidative stre …
Seasonal changes in markers of oxidative damage to lipids and DNA; correlations with seasonal variation in diet.
Smolková B, Dusinská M, Raslová K, McNeill G, Spustová V, Blazícek P, Horská A, Collins A. Smolková B, et al. Mutat Res. 2004 Jul 13;551(1-2):135-44. doi: 10.1016/j.mrfmmm.2004.02.021. Mutat Res. 2004. PMID: 15225588
Nutritional parameters and markers of oxidative stress were studied in three Slovak population groups: 46 survivors of myocardial infarction (MI group) and 48 healthy, normolipidemic subjects (NL), living in or near Bratislava; and 70 rural controls (RC group) living a mor …
Nutritional parameters and markers of oxidative stress were studied in three Slovak population groups: 46 survivors of myocardial infarction …
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