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A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis.
Beckett EL, Stevens RL, Jarnicki AG, Kim RY, Hanish I, Hansbro NG, Deane A, Keely S, Horvat JC, Yang M, Oliver BG, van Rooijen N, Inman MD, Adachi R, Soberman RJ, Hamadi S, Wark PA, Foster PS, Hansbro PM. Beckett EL, et al. Among authors: horvat jc. J Allergy Clin Immunol. 2013 Mar;131(3):752-62. doi: 10.1016/j.jaci.2012.11.053. Epub 2013 Feb 4. J Allergy Clin Immunol. 2013. PMID: 23380220 Free PMC article.
Mucosal production of uric acid by airway epithelial cells contributes to particulate matter-induced allergic sensitization.
Gold MJ, Hiebert PR, Park HY, Stefanowicz D, Le A, Starkey MR, Deane A, Brown AC, Liu G, Horvat JC, Ibrahim ZA, Sukkar MB, Hansbro PM, Carlsten C, VanEeden S, Sin DD, McNagny KM, Knight DA, Hirota JA. Gold MJ, et al. Among authors: horvat jc. Mucosal Immunol. 2016 May;9(3):809-20. doi: 10.1038/mi.2015.104. Epub 2015 Oct 28. Mucosal Immunol. 2016. PMID: 26509876 Free article.
MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase-mediated suppression of histone deacetylase 2.
Kim RY, Horvat JC, Pinkerton JW, Starkey MR, Essilfie AT, Mayall JR, Nair PM, Hansbro NG, Jones B, Haw TJ, Sunkara KP, Nguyen TH, Jarnicki AG, Keely S, Mattes J, Adcock IM, Foster PS, Hansbro PM. Kim RY, et al. Among authors: horvat jc. J Allergy Clin Immunol. 2017 Feb;139(2):519-532. doi: 10.1016/j.jaci.2016.04.038. Epub 2016 Jun 10. J Allergy Clin Immunol. 2017. PMID: 27448447 Free article.
IL-6 Drives Neutrophil-Mediated Pulmonary Inflammation Associated with Bacteremia in Murine Models of Colitis.
Mateer SW, Mathe A, Bruce J, Liu G, Maltby S, Fricker M, Goggins BJ, Tay HL, Marks E, Burns G, Kim RY, Minahan K, Walker MM, Callister RC, Foster PS, Horvat JC, Hansbro PM, Keely S. Mateer SW, et al. Among authors: horvat jc. Am J Pathol. 2018 Jul;188(7):1625-1639. doi: 10.1016/j.ajpath.2018.03.016. Epub 2018 Apr 22. Am J Pathol. 2018. PMID: 29684360 Free article.
Pharmacological HIF-1 stabilization promotes intestinal epithelial healing through regulation of α-integrin expression and function.
Goggins BJ, Minahan K, Sherwin S, Soh WS, Pryor J, Bruce J, Liu G, Mathe A, Knight D, Horvat JC, Walker MM, Keely S. Goggins BJ, et al. Among authors: horvat jc. Am J Physiol Gastrointest Liver Physiol. 2021 Apr 1;320(4):G420-G438. doi: 10.1152/ajpgi.00192.2020. Epub 2021 Jan 20. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 33470153 Free article.
135 results