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Implementing a unified approach to family-based tests of association.
Laird NM, Horvath S, Xu X. Laird NM, et al. Genet Epidemiol. 2000;19 Suppl 1:S36-42. doi: 10.1002/1098-2272(2000)19:1+<::AID-GEPI6>3.0.CO;2-M. Genet Epidemiol. 2000. PMID: 11055368
The family based association test method: strategies for studying general genotype--phenotype associations.
Horvath S, Xu X, Laird NM. Horvath S, et al. Eur J Hum Genet. 2001 Apr;9(4):301-6. doi: 10.1038/sj.ejhg.5200625. Eur J Hum Genet. 2001. PMID: 11313775
With possibly incomplete nuclear families, the family based association test (FBAT) method allows one to evaluate any test statistic that can be expressed as the sum of products (covariance) between an arbitrary function of an offspring's genotype with an arbitrary functio …
With possibly incomplete nuclear families, the family based association test (FBAT) method allows one to evaluate any test statistic that ca …
Family-based association test method: age of onset traits and covariates.
Horvath S, Wei E, Xu X, Palmer LJ, Baur M. Horvath S, et al. Genet Epidemiol. 2001;21 Suppl 1:S403-8. Genet Epidemiol. 2001. PMID: 11793708
To evaluate different FBAT statistics we used the software package FBAT, which allows one to evaluate any test statistic that can be expressed as the sum of products between an arbitrary function of an offspring's genotype with an arbitrary function of the offspring's
To evaluate different FBAT statistics we used the software package FBAT, which allows one to evaluate any test statistic that can be express …
A family-based test for correlation between gene expression and trait values.
Kraft P, Schadt E, Aten J, Horvath S. Kraft P, et al. Am J Hum Genet. 2003 May;72(5):1323-30. doi: 10.1086/375167. Epub 2003 Apr 8. Am J Hum Genet. 2003. PMID: 12687497 Free PMC article.
We demonstrate that the standard unstratified test based on Pearson's correlation coefficient can produce spurious results when applied to family data, and we present a stratified family expression association test (FEXAT). ...
We demonstrate that the standard unstratified test based on Pearson's correlation coefficient can produce spurious results when appli …
High concentrations of long interspersed nuclear element sequence distinguish monoallelically expressed genes.
Allen E, Horvath S, Tong F, Kraft P, Spiteri E, Riggs AD, Marahrens Y. Allen E, et al. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9940-5. doi: 10.1073/pnas.1737401100. Epub 2003 Aug 8. Proc Natl Acad Sci U S A. 2003. PMID: 12909712 Free PMC article.
The genetics of gene expression and gene mapping.
Kraft P, Horvath S. Kraft P, et al. Trends Biotechnol. 2003 Sep;21(9):377-8. doi: 10.1016/S0167-7799(03)00191-4. Trends Biotechnol. 2003. PMID: 12948667
Statistical methods for analyzing tissue microarray data.
Liu X, Minin V, Huang Y, Seligson DB, Horvath S. Liu X, et al. J Biopharm Stat. 2004 Aug;14(3):671-85. doi: 10.1081/BIP-200025657. J Biopharm Stat. 2004. PMID: 15468758
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