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308 results
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Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus.
Cowley MA, Smart JL, Rubinstein M, Cerdán MG, Diano S, Horvath TL, Cone RD, Low MJ. Cowley MA, et al. Among authors: horvath tl. Nature. 2001 May 24;411(6836):480-4. doi: 10.1038/35078085. Nature. 2001. PMID: 11373681
Heterogeneity in the neuropeptide Y-containing neurons of the rat arcuate nucleus: GABAergic and non-GABAergic subpopulations.
Horvath TL, Bechmann I, Naftolin F, Kalra SP, Leranth C. Horvath TL, et al. Brain Res. 1997 May 9;756(1-2):283-6. doi: 10.1016/s0006-8993(97)00184-4. Brain Res. 1997. PMID: 9187344
Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes.
Romanov RA, Zeisel A, Bakker J, Girach F, Hellysaz A, Tomer R, Alpár A, Mulder J, Clotman F, Keimpema E, Hsueh B, Crow AK, Martens H, Schwindling C, Calvigioni D, Bains JS, Máté Z, Szabó G, Yanagawa Y, Zhang MD, Rendeiro A, Farlik M, Uhlén M, Wulff P, Bock C, Broberger C, Deisseroth K, Hökfelt T, Linnarsson S, Horvath TL, Harkany T. Romanov RA, et al. Among authors: horvath tl. Nat Neurosci. 2017 Feb;20(2):176-188. doi: 10.1038/nn.4462. Epub 2016 Dec 19. Nat Neurosci. 2017. PMID: 27991900
Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding.
Kim JG, Suyama S, Koch M, Jin S, Argente-Arizon P, Argente J, Liu ZW, Zimmer MR, Jeong JK, Szigeti-Buck K, Gao Y, Garcia-Caceres C, Yi CX, Salmaso N, Vaccarino FM, Chowen J, Diano S, Dietrich MO, Tschöp MH, Horvath TL. Kim JG, et al. Among authors: horvath tl. Nat Neurosci. 2014 Jul;17(7):908-10. doi: 10.1038/nn.3725. Epub 2014 Jun 1. Nat Neurosci. 2014. PMID: 24880214 Free PMC article.
Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals.
Gao Q, Mezei G, Nie Y, Rao Y, Choi CS, Bechmann I, Leranth C, Toran-Allerand D, Priest CA, Roberts JL, Gao XB, Mobbs C, Shulman GI, Diano S, Horvath TL. Gao Q, et al. Among authors: horvath tl. Nat Med. 2007 Jan;13(1):89-94. doi: 10.1038/nm1525. Epub 2006 Dec 31. Nat Med. 2007. PMID: 17195839
Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.
Rathjen T, Yan X, Kononenko NL, Ku MC, Song K, Ferrarese L, Tarallo V, Puchkov D, Kochlamazashvili G, Brachs S, Varela L, Szigeti-Buck K, Yi CX, Schriever SC, Tattikota SG, Carlo AS, Moroni M, Siemens J, Heuser A, van der Weyden L, Birkenfeld AL, Niendorf T, Poulet JFA, Horvath TL, Tschöp MH, Heinig M, Trajkovski M, Haucke V, Poy MN. Rathjen T, et al. Among authors: horvath tl. Nat Neurosci. 2017 Aug;20(8):1096-1103. doi: 10.1038/nn.4590. Epub 2017 Jun 19. Nat Neurosci. 2017. PMID: 28628102 Free PMC article.
High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons.
Klöckener T, Hess S, Belgardt BF, Paeger L, Verhagen LA, Husch A, Sohn JW, Hampel B, Dhillon H, Zigman JM, Lowell BB, Williams KW, Elmquist JK, Horvath TL, Kloppenburg P, Brüning JC. Klöckener T, et al. Among authors: horvath tl. Nat Neurosci. 2011 Jun 5;14(7):911-8. doi: 10.1038/nn.2847. Nat Neurosci. 2011. PMID: 21642975 Free PMC article.
Intranasal epidermal growth factor treatment rescues neonatal brain injury.
Scafidi J, Hammond TR, Scafidi S, Ritter J, Jablonska B, Roncal M, Szigeti-Buck K, Coman D, Huang Y, McCarter RJ Jr, Hyder F, Horvath TL, Gallo V. Scafidi J, et al. Among authors: horvath tl. Nature. 2014 Feb 13;506(7487):230-4. doi: 10.1038/nature12880. Epub 2013 Dec 25. Nature. 2014. PMID: 24390343 Free PMC article.
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity.
Plum L, Ma X, Hampel B, Balthasar N, Coppari R, Münzberg H, Shanabrough M, Burdakov D, Rother E, Janoschek R, Alber J, Belgardt BF, Koch L, Seibler J, Schwenk F, Fekete C, Suzuki A, Mak TW, Krone W, Horvath TL, Ashcroft FM, Brüning JC. Plum L, et al. Among authors: horvath tl. J Clin Invest. 2006 Jul;116(7):1886-901. doi: 10.1172/JCI27123. Epub 2006 Jun 22. J Clin Invest. 2006. PMID: 16794735 Free PMC article.
AMPA receptors colocalize with neuropeptide-Y- and galanin-containing, but not with dopamine, neurons of the female rat arcuate nucleus: a semiquantitative immunohistochemical colocalization study.
Zsarnovszky A, Horvath TL, Naftolin F, Leranth C. Zsarnovszky A, et al. Among authors: horvath tl. Exp Brain Res. 2000 Aug;133(4):532-7. doi: 10.1007/s002210000425. Exp Brain Res. 2000. PMID: 10985687
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