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Page 1
Decreased mtDNA, oxidative stress, cardiomyopathy, and death from transgenic cardiac targeted human mutant polymerase gamma.
Lewis W, Day BJ, Kohler JJ, Hosseini SH, Chan SS, Green EC, Haase CP, Keebaugh ES, Long R, Ludaway T, Russ R, Steltzer J, Tioleco N, Santoianni R, Copeland WC. Lewis W, et al. Among authors: hosseini sh. Lab Invest. 2007 Apr;87(4):326-35. doi: 10.1038/labinvest.3700523. Epub 2006 Feb 19. Lab Invest. 2007. PMID: 17310215 Free PMC article.
Targeted transgenic overexpression of mitochondrial thymidine kinase (TK2) alters mitochondrial DNA (mtDNA) and mitochondrial polypeptide abundance: transgenic TK2, mtDNA, and antiretrovirals.
Hosseini SH, Kohler JJ, Haase CP, Tioleco N, Stuart T, Keebaugh E, Ludaway T, Russ R, Green E, Long R, Wang L, Eriksson S, Lewis W. Hosseini SH, et al. Am J Pathol. 2007 Mar;170(3):865-74. doi: 10.2353/ajpath.2007.060655. Am J Pathol. 2007. PMID: 17322372 Free PMC article.
Cardiac-targeted transgenic mutant mitochondrial enzymes: mtDNA defects, antiretroviral toxicity and cardiomyopathy.
Kohler JJ, Hosseini SH, Green E, Hoying-Brandt A, Cucoranu I, Haase CP, Russ R, Srivastava J, Ivey K, Ludaway T, Kapoor V, Abuin A, Shapoval A, Santoianni R, Saada A, Elpeleg O, Lewis W. Kohler JJ, et al. Among authors: hosseini sh. Cardiovasc Toxicol. 2008 Summer;8(2):57-69. doi: 10.1007/s12012-008-9015-1. Epub 2008 Apr 30. Cardiovasc Toxicol. 2008. PMID: 18446447 Free PMC article.
Murine cardiac mtDNA: effects of transgenic manipulation of nucleoside phosphorylation.
Kohler JJ, Hosseini SH, Cucoranu I, Hoying-Brandt A, Green E, Johnson D, Wittich B, Srivastava J, Ivey K, Fields E, Russ R, Raper CM, Santoianni R, Lewis W. Kohler JJ, et al. Among authors: hosseini sh. Lab Invest. 2009 Feb;89(2):122-30. doi: 10.1038/labinvest.2008.121. Epub 2008 Dec 15. Lab Invest. 2009. PMID: 19079325 Free PMC article.
Tenofovir renal toxicity targets mitochondria of renal proximal tubules.
Kohler JJ, Hosseini SH, Hoying-Brandt A, Green E, Johnson DM, Russ R, Tran D, Raper CM, Santoianni R, Lewis W. Kohler JJ, et al. Among authors: hosseini sh. Lab Invest. 2009 May;89(5):513-9. doi: 10.1038/labinvest.2009.14. Epub 2009 Mar 9. Lab Invest. 2009. PMID: 19274046 Free PMC article.
Transgenic cardiac-targeted overexpression of human thymidylate kinase.
Kohler JJ, Hosseini SH, Cucoranu I, Zhelyabovska O, Green E, Ivey K, Abuin A, Fields E, Hoying A, Russ R, Santoianni R, Raper CM, Yang Q, Lavie A, Lewis W. Kohler JJ, et al. Among authors: hosseini sh. Lab Invest. 2010 Mar;90(3):383-90. doi: 10.1038/labinvest.2009.146. Epub 2010 Jan 11. Lab Invest. 2010. PMID: 20065942 Free PMC article.
256 results