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Overcoming apoptosis deficiency of melanoma-hope for new therapeutic approaches.
Eberle J, Kurbanov BM, Hossini AM, Trefzer U, Fecker LF. Eberle J, et al. Among authors: hossini am. Drug Resist Updat. 2007 Dec;10(6):218-34. doi: 10.1016/j.drup.2007.09.001. Epub 2007 Dec 3. Drug Resist Updat. 2007. PMID: 18054518 Review.
Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells.
Plötz M, Gillissen B, Hossini AM, Daniel PT, Eberle J. Plötz M, et al. Among authors: hossini am. Cell Death Differ. 2012 Dec;19(12):1928-38. doi: 10.1038/cdd.2012.71. Epub 2012 Jun 15. Cell Death Differ. 2012. PMID: 22705850 Free PMC article.
The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis.
Raisova M, Hossini AM, Eberle J, Riebeling C, Wieder T, Sturm I, Daniel PT, Orfanos CE, Geilen CC. Raisova M, et al. Among authors: hossini am. J Invest Dermatol. 2001 Aug;117(2):333-40. doi: 10.1046/j.0022-202x.2001.01409.x. J Invest Dermatol. 2001. PMID: 11511312
A novel Bcl-x splice product, Bcl-xAK, triggers apoptosis in human melanoma cells without BH3 domain.
Hossini AM, Geilen CC, Fecker LF, Daniel PT, Eberle J. Hossini AM, et al. Oncogene. 2006 Apr 6;25(15):2160-9. doi: 10.1038/sj.onc.1209253. Oncogene. 2006. PMID: 16288206
Effect of 5alpha-dihydrotestosterone and testosterone on apoptosis in human dermal papilla cells.
Winiarska A, Mandt N, Kamp H, Hossini A, Seltmann H, Zouboulis CC, Blume-Peytavi U. Winiarska A, et al. Among authors: hossini a. Skin Pharmacol Physiol. 2006;19(6):311-21. doi: 10.1159/000095251. Epub 2006 Aug 23. Skin Pharmacol Physiol. 2006. PMID: 16931898
Pharmacological complement inhibition at the C3 convertase level promotes neuronal survival, neuroprotective intracerebral gene expression, and neurological outcome after traumatic brain injury.
Leinhase I, Schmidt OI, Thurman JM, Hossini AM, Rozanski M, Taha ME, Scheffler A, John T, Smith WR, Holers VM, Stahel PF. Leinhase I, et al. Among authors: hossini am. Exp Neurol. 2006 Jun;199(2):454-64. doi: 10.1016/j.expneurol.2006.01.033. Epub 2006 Mar 20. Exp Neurol. 2006. PMID: 16545803
Selective induction of apoptosis in melanoma cells by tyrosinase promoter-controlled CD95 ligand overexpression.
Fecker LF, Geilen CC, Hossini AM, Schwarz C, Fechner H, Bartlett DL, Orfanos CE, Eberle J. Fecker LF, et al. Among authors: hossini am. J Invest Dermatol. 2005 Jan;124(1):221-8. doi: 10.1111/j.0022-202X.2004.23572.x. J Invest Dermatol. 2005. PMID: 15654977
CD95/Fas signaling in human melanoma cells: conditional expression of CD95L/FasL overcomes the intrinsic apoptosis resistance of malignant melanoma and inhibits growth and progression of human melanoma xenotransplants.
Eberle J, Fecker LF, Hossini AM, Wieder T, Daniel PT, Orfanos CE, Geilen CC. Eberle J, et al. Among authors: hossini am. Oncogene. 2003 Dec 11;22(57):9131-41. doi: 10.1038/sj.onc.1207228. Oncogene. 2003. PMID: 14668794
Conditional expression of exogenous Bcl-X(S) triggers apoptosis in human melanoma cells in vitro and delays growth of melanoma xenografts.
Hossini AM, Eberle J, Fecker LF, Orfanos CE, Geilen CC. Hossini AM, et al. FEBS Lett. 2003 Oct 23;553(3):250-6. doi: 10.1016/s0014-5793(03)01017-2. FEBS Lett. 2003. PMID: 14572633
Bcl-2 overexpression prevents apoptosis induced by ceramidase inhibitors in malignant melanoma and HaCaT keratinocytes.
Raisova M, Goltz G, Bektas M, Bielawska A, Riebeling C, Hossini AM, Eberle J, Hannun YA, Orfanos CE, Geilen CC. Raisova M, et al. Among authors: hossini am. FEBS Lett. 2002 Apr 10;516(1-3):47-52. doi: 10.1016/s0014-5793(02)02472-9. FEBS Lett. 2002. PMID: 11959101
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