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Inflammation, stress, and diabetes.
Wellen KE, Hotamisligil GS. Wellen KE, et al. J Clin Invest. 2005 May;115(5):1111-9. doi: 10.1172/JCI25102. J Clin Invest. 2005. PMID: 15864338 Free PMC article. Review.
Immune Cell Intolerance for Excess Cholesterol.
Widenmaier SB, Hotamışlıgil GS. Widenmaier SB, et al. Immunity. 2016 Dec 20;45(6):1186-1188. doi: 10.1016/j.immuni.2016.12.006. Immunity. 2016. PMID: 28002726
Cell Signaling and Stress Responses.
Hotamisligil GS, Davis RJ. Hotamisligil GS, et al. Cold Spring Harb Perspect Biol. 2016 Oct 3;8(10):a006072. doi: 10.1101/cshperspect.a006072. Cold Spring Harb Perspect Biol. 2016. PMID: 27698029 Free PMC article. Review.
Metabolic functions of FABPs--mechanisms and therapeutic implications.
Hotamisligil GS, Bernlohr DA. Hotamisligil GS, et al. Nat Rev Endocrinol. 2015 Oct;11(10):592-605. doi: 10.1038/nrendo.2015.122. Epub 2015 Aug 11. Nat Rev Endocrinol. 2015. PMID: 26260145 Free PMC article. Review.
Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms.
Brozzi F, Nardelli TR, Lopes M, Millard I, Barthson J, Igoillo-Esteve M, Grieco FA, Villate O, Oliveira JM, Casimir M, Bugliani M, Engin F, Hotamisligil GS, Marchetti P, Eizirik DL. Brozzi F, et al. Diabetologia. 2015 Oct;58(10):2307-16. doi: 10.1007/s00125-015-3669-6. Epub 2015 Jun 23. Diabetologia. 2015. PMID: 26099855
Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity.
Fu S, Yalcin A, Lee GY, Li P, Fan J, Arruda AP, Pers BM, Yilmaz M, Eguchi K, Hotamisligil GS. Fu S, et al. Sci Transl Med. 2015 Jun 17;7(292):292ra98. doi: 10.1126/scitranslmed.aaa9134. Sci Transl Med. 2015. PMID: 26084805 Free PMC article.
Potential role for snoRNAs in PKR activation during metabolic stress.
Youssef OA, Safran SA, Nakamura T, Nix DA, Hotamisligil GS, Bass BL. Youssef OA, et al. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5023-8. doi: 10.1073/pnas.1424044112. Epub 2015 Apr 6. Proc Natl Acad Sci U S A. 2015. PMID: 25848059 Free PMC article.
Functional RNA interference (RNAi) screen identifies system A neutral amino acid transporter 2 (SNAT2) as a mediator of arsenic-induced endoplasmic reticulum stress.
Oh RS, Pan WC, Yalcin A, Zhang H, Guilarte TR, Hotamisligil GS, Christiani DC, Lu Q. Oh RS, et al. J Biol Chem. 2012 Feb 17;287(8):6025-34. doi: 10.1074/jbc.M111.311217. Epub 2012 Jan 3. J Biol Chem. 2012. PMID: 22215663 Free PMC article.
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