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Neuronal PTP1B regulates body weight, adiposity and leptin action.
Bence KK, Delibegovic M, Xue B, Gorgun CZ, Hotamisligil GS, Neel BG, Kahn BB. Bence KK, et al. Nat Med. 2006 Aug;12(8):917-24. doi: 10.1038/nm1435. Epub 2006 Jul 16. Nat Med. 2006. PMID: 16845389
Metabolic functions of FABPs--mechanisms and therapeutic implications.
Hotamisligil GS, Bernlohr DA. Hotamisligil GS, et al. Nat Rev Endocrinol. 2015 Oct;11(10):592-605. doi: 10.1038/nrendo.2015.122. Epub 2015 Aug 11. Nat Rev Endocrinol. 2015. PMID: 26260145 Free PMC article. Review.
The transcription factor GATA2 regulates differentiation of brown adipocytes.
Tsai J, Tong Q, Tan G, Chang AN, Orkin SH, Hotamisligil GS. Tsai J, et al. EMBO Rep. 2005 Sep;6(9):879-84. doi: 10.1038/sj.embor.7400490. EMBO Rep. 2005. PMID: 16082385 Free PMC article.
Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis.
Erbay E, Babaev VR, Mayers JR, Makowski L, Charles KN, Snitow ME, Fazio S, Wiest MM, Watkins SM, Linton MF, Hotamisligil GS. Erbay E, et al. Nat Med. 2009 Dec;15(12):1383-91. doi: 10.1038/nm.2067. Epub 2009 Nov 29. Nat Med. 2009. PMID: 19966778 Free PMC article.
Stressing the brain, fattening the body.
Yang L, Hotamisligil GS. Yang L, et al. Cell. 2008 Oct 3;135(1):20-2. doi: 10.1016/j.cell.2008.09.030. Cell. 2008. PMID: 18854151
Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance.
Tuncman G, Hirosumi J, Solinas G, Chang L, Karin M, Hotamisligil GS. Tuncman G, et al. Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10741-6. doi: 10.1073/pnas.0603509103. Epub 2006 Jul 3. Proc Natl Acad Sci U S A. 2006. PMID: 16818881 Free PMC article.
Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets.
Furuhashi M, Hotamisligil GS. Furuhashi M, et al. Nat Rev Drug Discov. 2008 Jun;7(6):489-503. doi: 10.1038/nrd2589. Nat Rev Drug Discov. 2008. PMID: 18511927 Free PMC article. Review.
Role of the fatty acid binding protein mal1 in obesity and insulin resistance.
Maeda K, Uysal KT, Makowski L, Görgün CZ, Atsumi G, Parker RA, Brüning J, Hertzel AV, Bernlohr DA, Hotamisligil GS. Maeda K, et al. Diabetes. 2003 Feb;52(2):300-7. doi: 10.2337/diabetes.52.2.300. Diabetes. 2003. PMID: 12540600 Free PMC article.
Regulation of adiponectin in human immunodeficiency virus-infected patients: relationship to body composition and metabolic indices.
Tong Q, Sankalé JL, Hadigan CM, Tan G, Rosenberg ES, Kanki PJ, Grinspoon SK, Hotamisligil GS. Tong Q, et al. J Clin Endocrinol Metab. 2003 Apr;88(4):1559-64. doi: 10.1210/jc.2002-021600. J Clin Endocrinol Metab. 2003. PMID: 12679439
Coordinated regulation of protein synthesis and degradation by mTORC1.
Zhang Y, Nicholatos J, Dreier JR, Ricoult SJ, Widenmaier SB, Hotamisligil GS, Kwiatkowski DJ, Manning BD. Zhang Y, et al. Nature. 2014 Sep 18;513(7518):440-3. doi: 10.1038/nature13492. Epub 2014 Jul 13. Nature. 2014. PMID: 25043031 Free PMC article.
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