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Inflammatory mechanisms in obesity.
Gregor MF, Hotamisligil GS. Gregor MF, et al. Annu Rev Immunol. 2011;29:415-45. doi: 10.1146/annurev-immunol-031210-101322. Annu Rev Immunol. 2011. PMID: 21219177 Review.
Defective STIM-mediated store operated Ca2+ entry in hepatocytes leads to metabolic dysfunction in obesity.
Arruda AP, Pers BM, Parlakgul G, G├╝ney E, Goh T, Cagampan E, Lee GY, Goncalves RL, Hotamisligil GS. Arruda AP, et al. Among authors: hotamisligil gs. Elife. 2017 Dec 15;6:e29968. doi: 10.7554/eLife.29968. Elife. 2017. PMID: 29243589 Free PMC article.
Cell Signaling and Stress Responses.
Hotamisligil GS, Davis RJ. Hotamisligil GS, et al. Cold Spring Harb Perspect Biol. 2016 Oct 3;8(10):a006072. doi: 10.1101/cshperspect.a006072. Cold Spring Harb Perspect Biol. 2016. PMID: 27698029 Free PMC article. Review.
Jnk1 Deficiency in Hematopoietic Cells Suppresses Macrophage Apoptosis and Increases Atherosclerosis in Low-Density Lipoprotein Receptor Null Mice.
Babaev VR, Yeung M, Erbay E, Ding L, Zhang Y, May JM, Fazio S, Hotamisligil GS, Linton MF. Babaev VR, et al. Arterioscler Thromb Vasc Biol. 2016 Jun;36(6):1122-31. doi: 10.1161/ATVBAHA.116.307580. Epub 2016 Apr 21. Arterioscler Thromb Vasc Biol. 2016. PMID: 27102962 Free PMC article.
Metabolic functions of FABPs--mechanisms and therapeutic implications.
Hotamisligil GS, Bernlohr DA. Hotamisligil GS, et al. Nat Rev Endocrinol. 2015 Oct;11(10):592-605. doi: 10.1038/nrendo.2015.122. Epub 2015 Aug 11. Nat Rev Endocrinol. 2015. PMID: 26260145 Free PMC article. Review.
Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms.
Brozzi F, Nardelli TR, Lopes M, Millard I, Barthson J, Igoillo-Esteve M, Grieco FA, Villate O, Oliveira JM, Casimir M, Bugliani M, Engin F, Hotamisligil GS, Marchetti P, Eizirik DL. Brozzi F, et al. Diabetologia. 2015 Oct;58(10):2307-16. doi: 10.1007/s00125-015-3669-6. Epub 2015 Jun 23. Diabetologia. 2015. PMID: 26099855
Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity.
Fu S, Yalcin A, Lee GY, Li P, Fan J, Arruda AP, Pers BM, Yilmaz M, Eguchi K, Hotamisligil GS. Fu S, et al. Sci Transl Med. 2015 Jun 17;7(292):292ra98. doi: 10.1126/scitranslmed.aaa9134. Sci Transl Med. 2015. PMID: 26084805 Free PMC article.
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