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Systematic analysis of bypass suppression of essential genes.
van Leeuwen J, Pons C, Tan G, Wang ZY, Hou J, Weile J, Gebbia M, Liang W, Shuteriqi E, Li Z, Lopes M, Ušaj M, Dos Santos Lopes A, van Lieshout N, Myers CL, Roth FP, Aloy P, Andrews BJ, Boone C. van Leeuwen J, et al. Among authors: hou j. Mol Syst Biol. 2020 Sep;16(9):e9828. doi: 10.15252/msb.20209828. Mol Syst Biol. 2020. PMID: 32939983 Free PMC article.
Environmental robustness of the global yeast genetic interaction network.
Costanzo M, Hou J, Messier V, Nelson J, Rahman M, VanderSluis B, Wang W, Pons C, Ross C, Ušaj M, San Luis BJ, Shuteriqi E, Koch EN, Aloy P, Myers CL, Boone C, Andrews B. Costanzo M, et al. Among authors: hou j. Science. 2021 May 7;372(6542):eabf8424. doi: 10.1126/science.abf8424. Science. 2021. PMID: 33958448 Free PMC article.
Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets.
Fu C, Zhang X, Veri AO, Iyer KR, Lash E, Xue A, Yan H, Revie NM, Wong C, Lin ZY, Polvi EJ, Liston SD, VanderSluis B, Hou J, Yashiroda Y, Gingras AC, Boone C, O'Meara TR, O'Meara MJ, Noble S, Robbins N, Myers CL, Cowen LE. Fu C, et al. Among authors: hou j. Nat Commun. 2021 Nov 11;12(1):6497. doi: 10.1038/s41467-021-26850-3. Nat Commun. 2021. PMID: 34764269 Free PMC article.
Domestication drives repeated evolution of sexual-asexual life cycle trade-offs in yeast.
Becerra-Rodríguez C, Thiele P, Brach G, Dutta A, Garin M, Tan G, Loegler V, Friedrich A, Andrews B, Boone C, Schacherer J, Hou J. Becerra-Rodríguez C, et al. Among authors: hou j. Proc Natl Acad Sci U S A. 2026 Jan 13;123(2):e2526682123. doi: 10.1073/pnas.2526682123. Epub 2026 Jan 8. Proc Natl Acad Sci U S A. 2026. PMID: 41505518 Free PMC article.
Population-scale chemical response revealed by a barcoded yeast collection.
Dutta A, Garin M, Loegler V, Brach G, Friedrich A, Yoshimura M, Hirano H, Osada H, Boone C, Yashiroda Y, Hou J, Schacherer J. Dutta A, et al. Among authors: hou j. Nat Commun. 2026 May 28. doi: 10.1038/s41467-026-73532-z. Online ahead of print. Nat Commun. 2026. PMID: 42209485 Free article.
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