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Regulation of proinflammatory monocyte activation by the kynurenine-AhR axis underlies immunometabolic control of depressive behavior in mice.
Zang X, Zheng X, Hou Y, Hu M, Wang H, Bao X, Zhou F, Wang G, Hao H. Zang X, et al. Among authors: hou y. FASEB J. 2018 Apr;32(4):1944-1956. doi: 10.1096/fj.201700853R. Epub 2018 Jan 5. FASEB J. 2018. PMID: 29183965
The findings in our study extend understanding of an immunologic effect of Kyn that links Trp metabolism and inflammatory signaling in depression pathology, with potential therapeutic implications for depressive disorders.-Zang, X., Zheng, X., Hou, Y., Hu, M., Wang, …
The findings in our study extend understanding of an immunologic effect of Kyn that links Trp metabolism and inflammatory signaling in depre …
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