Hou Z - Search Results

1

Small molecule modulator of protein disulfide isomerase attenuates mutant huntingtin toxicity and inhibits endoplasmic reticulum stress in a mouse model of Huntington's disease.

Zhou X, Li G, Kaplan A, Gaschler MM, Zhang X, Hou Z, Jiang M, Zott R, Cremers S, Stockwell BR, Duan W. Zhou X, et al. Among authors: hou z. Hum Mol Genet. 2018 May 1;27(9):1545-1555. doi: 10.1093/hmg/ddy061. Hum Mol Genet. 2018. PMID: 29462355 Free PMC article.

2

Longitudinal characterization of brain atrophy of a Huntington's disease mouse model by automated morphological analyses of magnetic resonance images.

Zhang J, Peng Q, Li Q, Jahanshad N, Hou Z, Jiang M, Masuda N, Langbehn DR, Miller MI, Mori S, Ross CA, Duan W. Zhang J, et al. Among authors: hou z. Neuroimage. 2010 Feb 1;49(3):2340-51. doi: 10.1016/j.neuroimage.2009.10.027. Epub 2009 Oct 19. Neuroimage. 2010. PMID: 19850133 Free PMC article.

3

Structural MRI detects progressive regional brain atrophy and neuroprotective effects in N171-82Q Huntington's disease mouse model.

Cheng Y, Peng Q, Hou Z, Aggarwal M, Zhang J, Mori S, Ross CA, Duan W. Cheng Y, et al. Among authors: hou z. Neuroimage. 2011 Jun 1;56(3):1027-34. doi: 10.1016/j.neuroimage.2011.02.022. Epub 2011 Feb 12. Neuroimage. 2011. PMID: 21320608 Free PMC article.

4

Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets.

Jiang M, Wang J, Fu J, Du L, Jeong H, West T, Xiang L, Peng Q, Hou Z, Cai H, Seredenina T, Arbez N, Zhu S, Sommers K, Qian J, Zhang J, Mori S, Yang XW, Tamashiro KL, Aja S, Moran TH, Luthi-Carter R, Martin B, Maudsley S, Mattson MP, Cichewicz RH, Ross CA, Holtzman DM, Krainc D, Duan W. Jiang M, et al. Among authors: hou z. Nat Med. 2011 Dec 18;18(1):153-8. doi: 10.1038/nm.2558. Nat Med. 2011. PMID: 22179319 Free PMC article.

5

Transgenic mouse model expressing the caspase 6 fragment of mutant huntingtin.

Waldron-Roby E, Ratovitski T, Wang X, Jiang M, Watkin E, Arbez N, Graham RK, Hayden MR, Hou Z, Mori S, Swing D, Pletnikov M, Duan W, Tessarollo L, Ross CA. Waldron-Roby E, et al. Among authors: hou z. J Neurosci. 2012 Jan 4;32(1):183-93. doi: 10.1523/JNEUROSCI.1305-11.2012. J Neurosci. 2012. PMID: 22219281 Free PMC article.

6

Spatiotemporal mapping of brain atrophy in mouse models of Huntington's disease using longitudinal in vivo magnetic resonance imaging.

Aggarwal M, Duan W, Hou Z, Rakesh N, Peng Q, Ross CA, Miller MI, Mori S, Zhang J. Aggarwal M, et al. Among authors: hou z. Neuroimage. 2012 May 1;60(4):2086-95. doi: 10.1016/j.neuroimage.2012.01.141. Epub 2012 Feb 9. Neuroimage. 2012. PMID: 22342677 Free PMC article.

7

Small-molecule TrkB receptor agonists improve motor function and extend survival in a mouse model of Huntington's disease.

Jiang M, Peng Q, Liu X, Jin J, Hou Z, Zhang J, Mori S, Ross CA, Ye K, Duan W. Jiang M, et al. Among authors: hou z. Hum Mol Genet. 2013 Jun 15;22(12):2462-70. doi: 10.1093/hmg/ddt098. Epub 2013 Feb 27. Hum Mol Genet. 2013. PMID: 23446639 Free PMC article.

8

Sirtuin 1 activator SRT2104 protects Huntington's disease mice.

Jiang M, Zheng J, Peng Q, Hou Z, Zhang J, Mori S, Ellis JL, Vlasuk GP, Fries H, Suri V, Duan W. Jiang M, et al. Among authors: hou z. Ann Clin Transl Neurol. 2014 Dec;1(12):1047-52. doi: 10.1002/acn3.135. Epub 2014 Oct 31. Ann Clin Transl Neurol. 2014. PMID: 25574479 Free PMC article.

9

Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease.

Jin J, Peng Q, Hou Z, Jiang M, Wang X, Langseth AJ, Tao M, Barker PB, Mori S, Bergles DE, Ross CA, Detloff PJ, Zhang J, Duan W. Jin J, et al. Among authors: hou z. Hum Mol Genet. 2015 May 1;24(9):2508-27. doi: 10.1093/hmg/ddv016. Epub 2015 Jan 21. Hum Mol Genet. 2015. PMID: 25609071 Free PMC article.

10

Characterization of Behavioral, Neuropathological, Brain Metabolic and Key Molecular Changes in zQ175 Knock-In Mouse Model of Huntington's Disease.

Peng Q, Wu B, Jiang M, Jin J, Hou Z, Zheng J, Zhang J, Duan W. Peng Q, et al. Among authors: hou z. PLoS One. 2016 Feb 9;11(2):e0148839. doi: 10.1371/journal.pone.0148839. eCollection 2016. PLoS One. 2016. PMID: 26859386 Free PMC article.

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