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The TOR pathway: a target for cancer therapy.
Bjornsti MA, Houghton PJ. Bjornsti MA, et al. Among authors: houghton pj. Nat Rev Cancer. 2004 May;4(5):335-48. doi: 10.1038/nrc1362. Nat Rev Cancer. 2004. PMID: 15122205 Review. No abstract available.
Amplification of the gli gene in childhood sarcomas.
Roberts WM, Douglass EC, Peiper SC, Houghton PJ, Look AT. Roberts WM, et al. Among authors: houghton pj. Cancer Res. 1989 Oct 1;49(19):5407-13. Cancer Res. 1989. PMID: 2766305
Relationship between dose rate of [6RS]Leucovorin administration, plasma concentrations of reduced folates, and pools of 5,10-methylenetetrahydrofolates and tetrahydrofolates in human colon adenocarcinoma xenografts.
Houghton JA, Williams LG, de Graaf SS, Cheshire PJ, Rodman JH, Maneval DC, Wainer IW, Jadaud P, Houghton PJ. Houghton JA, et al. Among authors: houghton pj. Cancer Res. 1990 Jun 15;50(12):3493-502. Cancer Res. 1990. PMID: 2140289
Predicted mechanisms of resistance to mTOR inhibitors.
Kurmasheva RT, Huang S, Houghton PJ. Kurmasheva RT, et al. Among authors: houghton pj. Br J Cancer. 2006 Oct 23;95(8):955-60. doi: 10.1038/sj.bjc.6603353. Epub 2006 Sep 5. Br J Cancer. 2006. PMID: 16953237 Free PMC article. Review.
Mechanisms of resistance to rapamycins.
Huang S, Houghton PJ. Huang S, et al. Among authors: houghton pj. Drug Resist Updat. 2001 Dec;4(6):378-91. doi: 10.1054/drup.2002.0227. Drug Resist Updat. 2001. PMID: 12030785 Review.
Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin.
Brunn GJ, Hudson CC, Sekulić A, Williams JM, Hosoi H, Houghton PJ, Lawrence JC Jr, Abraham RT. Brunn GJ, et al. Among authors: houghton pj. Science. 1997 Jul 4;277(5322):99-101. doi: 10.1126/science.277.5322.99. Science. 1997. PMID: 9204908
CGP 41251 and tamoxifen selectively inhibit mitogen-activated protein kinase activation and c-Fos phosphoprotein induction by substance P in human astrocytoma cells.
Luo W, Sharif TR, Houghton PJ, Sharif M. Luo W, et al. Among authors: houghton pj. Cell Growth Differ. 1997 Nov;8(11):1225-40. Cell Growth Differ. 1997. PMID: 9372245
Studies on the mechanism of resistance to rapamycin in human cancer cells.
Hosoi H, Dilling MB, Liu LN, Danks MK, Shikata T, Sekulic A, Abraham RT, Lawrence JC Jr, Houghton PJ. Hosoi H, et al. Among authors: houghton pj. Mol Pharmacol. 1998 Nov;54(5):815-24. doi: 10.1124/mol.54.5.815. Mol Pharmacol. 1998. PMID: 9804616
Influence of extracellular pH on the accumulation and cytotoxicity of N-(4-methylphenylsulfonyl)-N'-(4-chlorophenyl)urea in human cell lines.
Sosinski J, Chapin C, Thakar JH, Houghton PJ. Sosinski J, et al. Among authors: houghton pj. Cancer Commun. 1991;3(12):373-81. doi: 10.3727/095535491820873696. Cancer Commun. 1991. PMID: 16296003
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