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Establishment of human tumor xenografts in immunodeficient mice.
Morton CL, Houghton PJ. Morton CL, et al. Among authors: houghton pj. Nat Protoc. 2007;2(2):247-50. doi: 10.1038/nprot.2007.25. Nat Protoc. 2007. PMID: 17406581
Growth and characterization of childhood rhabdomyosarcomas as xenografts.
Houghton JA, Houghton PJ, Webber BL. Houghton JA, et al. Among authors: houghton pj. J Natl Cancer Inst. 1982 Mar;68(3):437-43. J Natl Cancer Inst. 1982. PMID: 6950170
Relationships between tumor responsiveness, vincristine pharmacokinetics and arrest of mitosis in human tumor xenografts.
Horton JK, Houghton PJ, Houghton JA. Horton JK, et al. Among authors: houghton pj, houghton ja. Biochem Pharmacol. 1988 Oct 15;37(20):3995-4000. doi: 10.1016/0006-2952(88)90085-8. Biochem Pharmacol. 1988. PMID: 3190743
Chemotherapy of childhood rhabdomyosarcomas growing as xenografts in immune-deprived mice.
Houghton JA, Houghton PJ, Green AA. Houghton JA, et al. Among authors: houghton pj. Cancer Res. 1982 Feb;42(2):535-9. Cancer Res. 1982. PMID: 7034923
Relationship between dose rate of [6RS]Leucovorin administration, plasma concentrations of reduced folates, and pools of 5,10-methylenetetrahydrofolates and tetrahydrofolates in human colon adenocarcinoma xenografts.
Houghton JA, Williams LG, de Graaf SS, Cheshire PJ, Rodman JH, Maneval DC, Wainer IW, Jadaud P, Houghton PJ. Houghton JA, et al. Among authors: houghton pj. Cancer Res. 1990 Jun 15;50(12):3493-502. Cancer Res. 1990. PMID: 2140289
Predicted mechanisms of resistance to mTOR inhibitors.
Kurmasheva RT, Huang S, Houghton PJ. Kurmasheva RT, et al. Among authors: houghton pj. Br J Cancer. 2006 Oct 23;95(8):955-60. doi: 10.1038/sj.bjc.6603353. Epub 2006 Sep 5. Br J Cancer. 2006. PMID: 16953237 Free PMC article. Review.
Mechanisms of resistance to rapamycins.
Huang S, Houghton PJ. Huang S, et al. Among authors: houghton pj. Drug Resist Updat. 2001 Dec;4(6):378-91. doi: 10.1054/drup.2002.0227. Drug Resist Updat. 2001. PMID: 12030785 Review.
Antitumor diarylsulfonylureas: novel agents with unfulfilled promise.
Houghton PJ, Houghton JA. Houghton PJ, et al. Among authors: houghton ja. Invest New Drugs. 1996;14(3):271-80. doi: 10.1007/BF00194530. Invest New Drugs. 1996. PMID: 8958182 Review.
Biochemical correlates of mTOR inhibition by the rapamycin ester CCI-779 and tumor growth inhibition.
Dudkin L, Dilling MB, Cheshire PJ, Harwood FC, Hollingshead M, Arbuck SG, Travis R, Sausville EA, Houghton PJ. Dudkin L, et al. Among authors: houghton pj. Clin Cancer Res. 2001 Jun;7(6):1758-64. Clin Cancer Res. 2001. PMID: 11410517
Relation between 9-aminocamptothecin systemic exposure and tumor response in human solid tumor xenografts.
Kirstein MN, Houghton PJ, Cheshire PJ, Richmond LB, Smith AK, Hanna SK, Stewart CF. Kirstein MN, et al. Among authors: houghton pj. Clin Cancer Res. 2001 Feb;7(2):358-66. Clin Cancer Res. 2001. PMID: 11234891
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