Houghton PJ - Search Results

1

Initial testing (stage 1) of the mTOR kinase inhibitor AZD8055 by the pediatric preclinical testing program.

Houghton PJ, Gorlick R, Kolb EA, Lock R, Carol H, Morton CL, Keir ST, Reynolds CP, Kang MH, Phelps D, Maris JM, Billups C, Smith MA. Houghton PJ, et al. Pediatr Blood Cancer. 2012 Feb;58(2):191-9. doi: 10.1002/pbc.22935. Epub 2011 Feb 18. Pediatr Blood Cancer. 2012. PMID: 21337679 Free PMC article.

2

Factors that influence the therapeutic activity of 5-fluorouracil [6RS]leucovorin combinations in colon adenocarcinoma xenografts.

Houghton JA, Williams LG, Loftin SK, Cheshire PJ, Morton CL, Houghton PJ, Dayan A, Jolivet J. Houghton JA, et al. Among authors: houghton pj. Cancer Chemother Pharmacol. 1992;30(6):423-32. doi: 10.1007/BF00685592. Cancer Chemother Pharmacol. 1992. PMID: 1394798

3

Activity of 9-dimethylaminomethyl-10-hydroxycamptothecin against pediatric and adult central nervous system tumor xenografts.

Friedman HS, Houghton PJ, Schold SC, Keir S, Bigner DD. Friedman HS, et al. Among authors: houghton pj. Cancer Chemother Pharmacol. 1994;34(2):171-4. doi: 10.1007/BF00685936. Cancer Chemother Pharmacol. 1994. PMID: 8194169

4

Therapeutic efficacy of the topoisomerase I inhibitor 7-ethyl-10-(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothecin against pediatric and adult central nervous system tumor xenografts.

Hare CB, Elion GB, Houghton PJ, Houghton JA, Keir S, Marcelli SL, Bigner DD, Friedman HS. Hare CB, et al. Among authors: houghton ja, houghton pj. Cancer Chemother Pharmacol. 1997;39(3):187-91. doi: 10.1007/s002800050558. Cancer Chemother Pharmacol. 1997. PMID: 8996518

5

Comparison of activation of CPT-11 by rabbit and human carboxylesterases for use in enzyme/prodrug therapy.

Danks MK, Morton CL, Krull EJ, Cheshire PJ, Richmond LB, Naeve CW, Pawlik CA, Houghton PJ, Potter PM. Danks MK, et al. Among authors: houghton pj. Clin Cancer Res. 1999 Apr;5(4):917-24. Clin Cancer Res. 1999. PMID: 10213229

6

Schedule-dependent activity of irinotecan plus BCNU against malignant glioma xenografts.

Castellino RC, Elion GB, Keir ST, Houghton PJ, Johnson SP, Bigner DD, Friedman HS. Castellino RC, et al. Among authors: houghton pj. Cancer Chemother Pharmacol. 2000;45(4):345-9. doi: 10.1007/s002800050050. Cancer Chemother Pharmacol. 2000. PMID: 10755324

7

Activity of irofulven (6-hydroxymethylacylfulvene) in the treatment of glioblastoma multiforme-derived xenografts in athymic mice.

Friedman HS, Keir ST, Houghton PJ, Lawless AA, Bigner DD, Waters SJ. Friedman HS, et al. Among authors: houghton pj. Cancer Chemother Pharmacol. 2001 Nov;48(5):413-6. doi: 10.1007/s002800100358. Cancer Chemother Pharmacol. 2001. PMID: 11761460

8

Efficacy and toxicity of a virus-directed enzyme prodrug therapy purging method: preclinical assessment and application to bone marrow samples from neuroblastoma patients.

Wagner LM, Guichard SM, Burger RA, Morton CL, Straign CM, Ashmun RA, Harris LC, Houghton PJ, Potter PM, Danks MK. Wagner LM, et al. Among authors: houghton pj. Cancer Res. 2002 Sep 1;62(17):5001-7. Cancer Res. 2002. PMID: 12208753

9

Relation between Irofulven (MGI-114) systemic exposure and tumor response in human solid tumor xenografts.

Leggas M, Stewart CF, Woo MH, Fouladi M, Cheshire PJ, Peterson JK, Friedman HS, Billups C, Houghton PJ. Leggas M, et al. Among authors: houghton pj. Clin Cancer Res. 2002 Sep;8(9):3000-7. Clin Cancer Res. 2002. PMID: 12231547

10

Testing of new agents in childhood cancer preclinical models: meeting summary.

Houghton PJ, Adamson PC, Blaney S, Fine HA, Gorlick R, Haber M, Helman L, Hirschfeld S, Hollingshead MG, Israel MA, Lock RB, Maris JM, Merlino G, Patterson W, Reynolds CP, Shannon K, Yu A, Yu J, Smith MA. Houghton PJ, et al. Clin Cancer Res. 2002 Dec;8(12):3646-57. Clin Cancer Res. 2002. PMID: 12473573

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