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90 results
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Reduced response to the formalin test and lowered spinal NMDA glutamate receptor binding in adenosine A2A receptor knockout mice.
Hussey MJ, Clarke GD, Ledent C, Hourani SMO, Kitchen I. Hussey MJ, et al. Among authors: hourani smo. Pain. 2007 Jun;129(3):287-294. doi: 10.1016/j.pain.2006.10.014. Epub 2006 Nov 28. Pain. 2007. PMID: 17134834
Genetic deletion of the adenosine A(2A) receptor prevents nicotine-induced upregulation of α7, but not α4β2* nicotinic acetylcholine receptor binding in the brain.
Metaxas A, Al-Hasani R, Farshim P, Tubby K, Berwick A, Ledent C, Hourani S, Kitchen I, Bailey A. Metaxas A, et al. Neuropharmacology. 2013 Aug;71:228-36. doi: 10.1016/j.neuropharm.2013.03.023. Epub 2013 Apr 11. Neuropharmacology. 2013. PMID: 23583933
In vivo dopaminergic and behavioral responses to acute cocaine are altered in adenosine A(2A) receptor knockout mice.
Wells L, Opacka-Juffry J, Fisher D, Ledent C, Hourani S, Kitchen I. Wells L, et al. Synapse. 2012 May;66(5):383-90. doi: 10.1002/syn.21527. Epub 2012 Feb 15. Synapse. 2012. PMID: 22213208
Inactivation of adenosine A2A receptor attenuates basal and angiotensin II-induced ROS production by Nox2 in endothelial cells.
Thakur S, Du J, Hourani S, Ledent C, Li JM. Thakur S, et al. J Biol Chem. 2010 Dec 17;285(51):40104-13. doi: 10.1074/jbc.M110.184606. Epub 2010 Oct 12. J Biol Chem. 2010. PMID: 20940302 Free PMC article.
Characterization of [3H]ZM 241385 binding in wild-type and adenosine A2A receptor knockout mice.
Kelly M, Bailey A, Ledent C, Kitchen I, Hourani S. Kelly M, et al. Eur J Pharmacol. 2004 Nov 3;504(1-2):55-9. doi: 10.1016/j.ejphar.2004.09.052. Eur J Pharmacol. 2004. PMID: 15507221
Adenosine A2A receptor signaling regulation of cardiac NADPH oxidase activity.
Ribé D, Sawbridge D, Thakur S, Hussey M, Ledent C, Kitchen I, Hourani S, Li JM. Ribé D, et al. Free Radic Biol Med. 2008 Apr 1;44(7):1433-42. doi: 10.1016/j.freeradbiomed.2007.12.035. Epub 2008 Jan 5. Free Radic Biol Med. 2008. PMID: 18206127 Free PMC article.
Emotional Impairment and Persistent Upregulation of mGlu5 Receptor following Morphine Abstinence: Implications of an mGlu5-MOPr Interaction.
Zanos P, Georgiou P, Gonzalez LR, Hourani S, Chen Y, Kitchen I, Kieffer BL, Winsky-Sommerer R, Bailey A. Zanos P, et al. Int J Neuropsychopharmacol. 2016 Jul 5;19(7):pyw011. doi: 10.1093/ijnp/pyw011. Print 2016 Jul. Int J Neuropsychopharmacol. 2016. PMID: 26861145 Free PMC article.
A critical role of striatal A2A R-mGlu5 R interactions in modulating the psychomotor and drug-seeking effects of methamphetamine.
Wright SR, Zanos P, Georgiou P, Yoo JH, Ledent C, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A. Wright SR, et al. Among authors: hourani sm. Addict Biol. 2016 Jul;21(4):811-25. doi: 10.1111/adb.12259. Epub 2015 May 15. Addict Biol. 2016. PMID: 25975203
Chronic methamphetamine treatment induces oxytocin receptor up-regulation in the amygdala and hypothalamus via an adenosine A2A receptor-independent mechanism.
Zanos P, Wright SR, Georgiou P, Yoo JH, Ledent C, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A. Zanos P, et al. Among authors: hourani sm. Pharmacol Biochem Behav. 2014 Apr;119:72-9. doi: 10.1016/j.pbb.2013.05.009. Epub 2013 May 13. Pharmacol Biochem Behav. 2014. PMID: 23680573
Relaxation of mouse isolated aorta to adenosine and its analogues does not involve adenosine A(1), A(2) or A(3) receptors.
Prentice D, Boon K, Hourani S. Prentice D, et al. Eur J Pharmacol. 2001 Mar;415(2-3):251-5. doi: 10.1016/s0014-2999(01)00841-x. Eur J Pharmacol. 2001. PMID: 11275007
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