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Transforming growth factor-beta1 promotes the morphological and functional differentiation of the myofibroblast.
Vaughan MB, Howard EW, Tomasek JJ. Vaughan MB, et al. Among authors: howard ew. Exp Cell Res. 2000 May 25;257(1):180-9. doi: 10.1006/excr.2000.4869. Exp Cell Res. 2000. PMID: 10854066
Whole animal knockout of smooth muscle alpha-actin does not alter excisional wound healing or the fibroblast-to-myofibroblast transition.
Tomasek JJ, Haaksma CJ, Schwartz RJ, Howard EW. Tomasek JJ, et al. Among authors: howard ew. Wound Repair Regen. 2013 Jan-Feb;21(1):166-76. doi: 10.1111/wrr.12001. Epub 2012 Dec 18. Wound Repair Regen. 2013. PMID: 23253249 Free PMC article.
Tissue inhibitor of metalloproteinases-1 is decreased and activated gelatinases are increased in chronic wounds.
Bullen EC, Longaker MT, Updike DL, Benton R, Ladin D, Hou Z, Howard EW. Bullen EC, et al. Among authors: howard ew. J Invest Dermatol. 1995 Feb;104(2):236-40. doi: 10.1111/1523-1747.ep12612786. J Invest Dermatol. 1995. PMID: 7829879
Effect of wavelength on low-intensity laser irradiation-stimulated cell proliferation in vitro.
Moore P, Ridgway TD, Higbee RG, Howard EW, Lucroy MD. Moore P, et al. Among authors: howard ew. Lasers Surg Med. 2005 Jan;36(1):8-12. doi: 10.1002/lsm.20117. Lasers Surg Med. 2005. PMID: 15662631
Enhanced motility of KGF-transfected breast cancer cells.
Zang XP, Bullen EC, Manjeshwar S, Jupe ER, Howard EW, Pento JT. Zang XP, et al. Among authors: howard ew. Anticancer Res. 2006 Mar-Apr;26(2A):961-6. Anticancer Res. 2006. PMID: 16619493
Transcriptional and posttranscriptional regulation of angiopoietin-2 expression mediated by IGF and PDGF in vascular smooth muscle cells.
Phelps ED, Updike DL, Bullen EC, Grammas P, Howard EW. Phelps ED, et al. Among authors: howard ew. Am J Physiol Cell Physiol. 2006 Feb;290(2):C352-61. doi: 10.1152/ajpcell.00050.2005. Epub 2005 Sep 21. Am J Physiol Cell Physiol. 2006. PMID: 16176970
MMP-2 expression by fibroblasts is suppressed by the myofibroblast phenotype.
Howard EW, Crider BJ, Updike DL, Bullen EC, Parks EE, Haaksma CJ, Sherry DM, Tomasek JJ. Howard EW, et al. Exp Cell Res. 2012 Aug 1;318(13):1542-53. doi: 10.1016/j.yexcr.2012.03.007. Epub 2012 Mar 17. Exp Cell Res. 2012. PMID: 22449415 Free PMC article.
TGF-beta suppresses the upregulation of MMP-2 by vascular smooth muscle cells in response to PDGF-BB.
Risinger GM Jr, Updike DL, Bullen EC, Tomasek JJ, Howard EW. Risinger GM Jr, et al. Among authors: howard ew. Am J Physiol Cell Physiol. 2010 Jan;298(1):C191-201. doi: 10.1152/ajpcell.00417.2008. Epub 2009 Oct 21. Am J Physiol Cell Physiol. 2010. PMID: 19846754 Free PMC article.
A simple method for using silicone elastomer masks for quantitative analysis of cell migration without cellular damage or substrate disruption.
Sherry DM, Parks EE, Bullen EC, Updike DL, Howard EW. Sherry DM, et al. Among authors: howard ew. Cell Adh Migr. 2013 Nov-Dec;7(6):469-75. doi: 10.4161/cam.27294. Epub 2013 Dec 2. Cell Adh Migr. 2013. PMID: 24430202 Free PMC article.
Myocardin-related transcription factors A and B are key regulators of TGF-β1-induced fibroblast to myofibroblast differentiation.
Crider BJ, Risinger GM Jr, Haaksma CJ, Howard EW, Tomasek JJ. Crider BJ, et al. Among authors: howard ew. J Invest Dermatol. 2011 Dec;131(12):2378-85. doi: 10.1038/jid.2011.219. Epub 2011 Jul 21. J Invest Dermatol. 2011. PMID: 21776010 Free PMC article.
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