Howard Hughes Medical Institute/United States[Grant Number] - Search Results

Year	Number of Results
1978	1
1985	2
1988	1
1989	2
1990	7
1991	4
1992	8
1993	10
1994	12
1995	5
1996	8
1997	14
1998	9
1999	21
2000	23
2001	29
2002	36
2003	46
2004	79
2005	73
2006	129
2007	320
2008	2378
2009	2750
2010	3026
2011	3128
2012	3096
2013	3114
2014	2990
2015	2837
2016	1994
2017	1572
2018	1803
2019	1433
2020	1465
2021	158

1

CRISPR-Cas guides the future of genetic engineering.

Knott GJ, Doudna JA. Knott GJ, et al. Science. 2018 Aug 31;361(6405):866-869. doi: 10.1126/science.aat5011. Science. 2018. PMID: 30166482 Free PMC article. Review.

2

Unique features of long non-coding RNA biogenesis and function.

Quinn JJ, Chang HY. Quinn JJ, et al. Nat Rev Genet. 2016 Jan;17(1):47-62. doi: 10.1038/nrg.2015.10. Nat Rev Genet. 2016. PMID: 26666209 Review.

3

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity.

Chen JS, Ma E, Harrington LB, Da Costa M, Tian X, Palefsky JM, Doudna JA. Chen JS, et al. Science. 2018 Apr 27;360(6387):436-439. doi: 10.1126/science.aar6245. Epub 2018 Feb 15. Science. 2018. PMID: 29449511 Free PMC article.

4

The microbiota in adaptive immune homeostasis and disease.

Honda K, Littman DR. Honda K, et al. Nature. 2016 Jul 7;535(7610):75-84. doi: 10.1038/nature18848. Nature. 2016. PMID: 27383982 Review.

5

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Shi J, Zhao Y, Wang K, Shi X, Wang Y, Huang H, Zhuang Y, Cai T, Wang F, Shao F. Shi J, et al. Nature. 2015 Oct 29;526(7575):660-5. doi: 10.1038/nature15514. Epub 2015 Sep 16. Nature. 2015. PMID: 26375003

6

Hallmarks of pluripotency.

De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant J, Wernig M, Park PJ, Daley GQ. De Los Angeles A, et al. Nature. 2015 Sep 24;525(7570):469-78. doi: 10.1038/nature15515. Nature. 2015. PMID: 26399828 Review.

7

Engrams and circuits crucial for systems consolidation of a memory.

Kitamura T, Ogawa SK, Roy DS, Okuyama T, Morrissey MD, Smith LM, Redondo RL, Tonegawa S. Kitamura T, et al. Science. 2017 Apr 7;356(6333):73-78. doi: 10.1126/science.aam6808. Science. 2017. PMID: 28386011 Free PMC article.

8

Memory Engram Cells Have Come of Age.

Tonegawa S, Liu X, Ramirez S, Redondo R. Tonegawa S, et al. Neuron. 2015 Sep 2;87(5):918-31. doi: 10.1016/j.neuron.2015.08.002. Neuron. 2015. PMID: 26335640 Free article. Review.

9

Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection.

Huang CH, Lee KC, Doudna JA. Huang CH, et al. Trends Cancer. 2018 Jul;4(7):499-512. doi: 10.1016/j.trecan.2018.05.006. Epub 2018 Jun 13. Trends Cancer. 2018. PMID: 29937048 Free PMC article. Review.

10

Ventral CA1 neurons store social memory.

Okuyama T, Kitamura T, Roy DS, Itohara S, Tonegawa S. Okuyama T, et al. Science. 2016 Sep 30;353(6307):1536-1541. doi: 10.1126/science.aaf7003. Science. 2016. PMID: 27708103 Free PMC article.

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